CAJ | 학술논문

目的：探讨幼年型类风湿性关节炎临床分型以及免疫学特点。方法回顾性分析我院2013年1月至2014年1月儿科收治的幼年型类风湿性关节炎（ JRA）患儿38例为研究组，同时选取30健康幼儿为对照组，对研究组患儿的临床表现以及检查结果等加以分析。结果38例患儿临床分型方面，全身型22例，多关节型11例，少关节型5例，研究组患儿的T淋巴细胞亚群和IL－2同对照组研究对象相比存在显著不同，差异有统计学意义（ P＜0．05）。结论 JRA的分型诊断主要通过临床特征，同时排除患儿的其他系统疾病，并应用其他辅助检查了解该病的活动性，同时在JRA的治疗方面应当长期规范治疗，从而避免影响患儿的预后。
목적：탐토유년형류풍습성관절염림상분형이급면역학특점。방법회고성분석아원2013년1월지2014년1월인과수치적유년형류풍습성관절염（ JRA）환인38례위연구조，동시선취30건강유인위대조조，대연구조환인적림상표현이급검사결과등가이분석。결과38례환인림상분형방면，전신형22례，다관절형11례，소관절형5례，연구조환인적T림파세포아군화IL－2동대조조연구대상상비존재현저불동，차이유통계학의의（ P＜0．05）。결론 JRA적분형진단주요통과림상특정，동시배제환인적기타계통질병，병응용기타보조검사료해해병적활동성，동시재JRA적치료방면응당장기규범치료，종이피면영향환인적예후。
Objective To investigate the clinical classification of juvenile rheumatoid arthritis and immunological characteristics.Methods A retrospective analysis was done on the datas of 38 casesof pediatric juvenile rheumatoid arthritis ( JRA) admitted toour hospital during January 2013 and January 2014, and 30 healthy children were selected as the control group, the clinical manifestations and detection findings of children were analyzed.Results Among the 38 cases of children, 22 cases of systemic type, 11 cases of polyarticular type, and 5 cases of oligoarticular type.Differences of T lymphocyte subsets and IL -2 between the two group was statistically significant (P<0.05).Conclusions The diagnosis of JRAtype primarily by clinical features and excluding other diseases in children and applying other supplementary examination to understand the disease activity, the treatment for JRA should be long-term therapy and specification, avoiding influence the prognosis of children.