中国医学创新
中國醫學創新
중국의학창신
Medical Innovation of China
2015年
26期
127-129,130
,共4页
抗感染药物%药物不良反应
抗感染藥物%藥物不良反應
항감염약물%약물불량반응
Anti-infectives%Adverse drug reactions
目的:分析本院抗感染药物不良反应(ADR)的特点,并进行针对性分析。方法:本院门诊收集的抗感染ADR报告162例,按患者性别年龄比例、给药方式、药物种类、临床表现及结果等进行分析。结果:在162例ADR患者中,静脉输液给药引起ADR 124例(76.54%)居首位,头孢菌素类引起的ADR 106例(65.43%)居首位,在临床表现中,以皮肤及其附件的损害63例(38.89%)为主。治愈145例(89.51%),好转17例(10.49%)。未出现后遗症和死亡病例。因果关联性评价:肯定7例(4.32%),很有可能115例(70.99%),可能的为40例(24.69%)。结论:在临床上对一定要谨慎使用抗感染药物,以避免和减少ADR对于严重的抗感染药物不良反应,要随时做好急救准备。
目的:分析本院抗感染藥物不良反應(ADR)的特點,併進行針對性分析。方法:本院門診收集的抗感染ADR報告162例,按患者性彆年齡比例、給藥方式、藥物種類、臨床錶現及結果等進行分析。結果:在162例ADR患者中,靜脈輸液給藥引起ADR 124例(76.54%)居首位,頭孢菌素類引起的ADR 106例(65.43%)居首位,在臨床錶現中,以皮膚及其附件的損害63例(38.89%)為主。治愈145例(89.51%),好轉17例(10.49%)。未齣現後遺癥和死亡病例。因果關聯性評價:肯定7例(4.32%),很有可能115例(70.99%),可能的為40例(24.69%)。結論:在臨床上對一定要謹慎使用抗感染藥物,以避免和減少ADR對于嚴重的抗感染藥物不良反應,要隨時做好急救準備。
목적:분석본원항감염약물불량반응(ADR)적특점,병진행침대성분석。방법:본원문진수집적항감염ADR보고162례,안환자성별년령비례、급약방식、약물충류、림상표현급결과등진행분석。결과:재162례ADR환자중,정맥수액급약인기ADR 124례(76.54%)거수위,두포균소류인기적ADR 106례(65.43%)거수위,재림상표현중,이피부급기부건적손해63례(38.89%)위주。치유145례(89.51%),호전17례(10.49%)。미출현후유증화사망병례。인과관련성평개:긍정7례(4.32%),흔유가능115례(70.99%),가능적위40례(24.69%)。결론:재림상상대일정요근신사용항감염약물,이피면화감소ADR대우엄중적항감염약물불량반응,요수시주호급구준비。
Objective:To analyze the hospital anti-infectives adverse reactions (ADR) characteristics, and targeted analysis.Method:Outpatients collected 162 cases of anti-infective ADR reports, by patient sex and age, mode of administration, drug type, clinical presentation and outcome were analyzed.Result:The result in 162 cases of ADR, the administration of intravenous fluids caused ADR was 124 cases (76.54%) in the first place, cephalosporins class caused ADR was 106 cases (65.43%) in the first place, in the clinical manifestations, skin and its annexes damage was 63 cases (38.89%). Cured in 145 cases (89.51%), improved in 17 cases (10.49%);no sequelae and deaths occurred. Causality assessment:positive in 7 cases (4.32%), most likely in 115 cases (70.99%), the possible in 41 cases (25.31%). Conclusion:On clinical anti-infective drugs must be used with caution in order to avoid and reduce the ADR for serious adverse reactions should always anti-infectives make emergency preparations.