现代肿瘤医学
現代腫瘤醫學
현대종류의학
Journal of Modern Oncology
2015年
19期
2828-2831
,共4页
刘北涛%崔云静%王宇飞%周本健
劉北濤%崔雲靜%王宇飛%週本健
류북도%최운정%왕우비%주본건
瑞芬太尼%丙泊酚%靶控输注%脑肿瘤%手术
瑞芬太尼%丙泊酚%靶控輸註%腦腫瘤%手術
서분태니%병박분%파공수주%뇌종류%수술
remifentanil%propofol%target - controlled infusion%brain tumor%surgery
目的：探讨瑞芬太尼复合丙泊酚靶控输注对脑肿瘤围手术的影响，为脑肿瘤患者实施最佳麻醉方法。方法：选取脑肿瘤患者134例，随机分为两组。对照组患者采取丙泊酚、瑞芬太尼、维库溴铵诱导麻醉后，静脉复合吸入异氟醚维持麻醉；观察组患者实施瑞芬太尼复合丙泊酚靶控注射麻醉。结果：麻醉诱导期观察组患者 SBP、DBP 最低分别为（101.59±10.26）mmHg 和（54.43±5.27）mmHg，对照组分别为（91.65±9.22） mmHg 和（47.36±4.52）mmHg，观察组明显高于对照组。术后观察组患者定向力恢复时间为（16.32±2.01） min，对照组为（22.76±2.83）min，观察组明显短于对照组。观察组患者拔管后即刻、离开手术室时以及拔管后1h OAAS 得分分别为3.19±0.30、4.12±0.23和4.52±0.42，对照组分别为2.23±0.18、3.28±0.31和4.01±0.36，观察组患者拔管后1h MMSE 得分为28.15±1.02，对照组为26.92±1.73，观察组明显高于对照组，上述比较两组差异有统计学意义（P ＜0.05）。结论：瑞芬太尼复合丙泊酚靶控输注与静吸复合麻醉相比诱导期生命体征更为平稳，术后苏醒质量更高，因此也更适合脑肿瘤手术患者麻醉。
目的：探討瑞芬太尼複閤丙泊酚靶控輸註對腦腫瘤圍手術的影響，為腦腫瘤患者實施最佳痳醉方法。方法：選取腦腫瘤患者134例，隨機分為兩組。對照組患者採取丙泊酚、瑞芬太尼、維庫溴銨誘導痳醉後，靜脈複閤吸入異氟醚維持痳醉；觀察組患者實施瑞芬太尼複閤丙泊酚靶控註射痳醉。結果：痳醉誘導期觀察組患者 SBP、DBP 最低分彆為（101.59±10.26）mmHg 和（54.43±5.27）mmHg，對照組分彆為（91.65±9.22） mmHg 和（47.36±4.52）mmHg，觀察組明顯高于對照組。術後觀察組患者定嚮力恢複時間為（16.32±2.01） min，對照組為（22.76±2.83）min，觀察組明顯短于對照組。觀察組患者拔管後即刻、離開手術室時以及拔管後1h OAAS 得分分彆為3.19±0.30、4.12±0.23和4.52±0.42，對照組分彆為2.23±0.18、3.28±0.31和4.01±0.36，觀察組患者拔管後1h MMSE 得分為28.15±1.02，對照組為26.92±1.73，觀察組明顯高于對照組，上述比較兩組差異有統計學意義（P ＜0.05）。結論：瑞芬太尼複閤丙泊酚靶控輸註與靜吸複閤痳醉相比誘導期生命體徵更為平穩，術後囌醒質量更高，因此也更適閤腦腫瘤手術患者痳醉。
목적：탐토서분태니복합병박분파공수주대뇌종류위수술적영향，위뇌종류환자실시최가마취방법。방법：선취뇌종류환자134례，수궤분위량조。대조조환자채취병박분、서분태니、유고추안유도마취후，정맥복합흡입이불미유지마취；관찰조환자실시서분태니복합병박분파공주사마취。결과：마취유도기관찰조환자 SBP、DBP 최저분별위（101.59±10.26）mmHg 화（54.43±5.27）mmHg，대조조분별위（91.65±9.22） mmHg 화（47.36±4.52）mmHg，관찰조명현고우대조조。술후관찰조환자정향력회복시간위（16.32±2.01） min，대조조위（22.76±2.83）min，관찰조명현단우대조조。관찰조환자발관후즉각、리개수술실시이급발관후1h OAAS 득분분별위3.19±0.30、4.12±0.23화4.52±0.42，대조조분별위2.23±0.18、3.28±0.31화4.01±0.36，관찰조환자발관후1h MMSE 득분위28.15±1.02，대조조위26.92±1.73，관찰조명현고우대조조，상술비교량조차이유통계학의의（P ＜0.05）。결론：서분태니복합병박분파공수주여정흡복합마취상비유도기생명체정경위평은，술후소성질량경고，인차야경괄합뇌종류수술환자마취。
Objective:To investigate perioperative influence on paitents with remifentanil and propofol by target -controlled infusion. Methods:All 134 brain tumor patients were selected,were randomly divided into two groups. Con-trol group were anaesthetized with propofol,remifentaniland vecuronium,and intravenous anesthesia was maintained with isoflurane,intravenous anesthesia was maintained with isoflurane,observation group were anaesthetized with remifentanil and propofol by target - controlled injection of anesthesia. Results:The induction of anesthesia in patients in the observation group SBP,DBP were lowest respectively(101. 59 ± 10. 26)mmHg and(54. 43 ± 5. 27)mmHg,re-spectively,in the control group were(91. 65 ± 9. 22)mmHg and(47. 36 ± 4. 52)mmHg,the observation group was significantly higher in the control group. Disorientation postoperative recovery time in the observation group was (16. 32 ± 2. 01)min,the control group(22. 76 ± 2. 83)min,the observation group was significantly shorter than the control group,the observation group were extubated immediately after leaving the operating room when and 1hOAAS score after extubation were 3. 19 ± 0. 30,4. 12 ± 0. 23 and 4. 52 ± 0 . 42 ,respectively,in the control group 2. 23 ± 0. 18,3. 28 ± 0. 31 and 4. 01 ± 0. 36,was observed patients after extubation 1h MMSE score 28. 15 ± 1. 02,the control group 26. 92 ± 1. 73,the observation group was significantly higher(P < 0. 05). Conclusion:The remifentanil target - controlled infusion of propofol and inhalation anesthesia induction period compared to a more stable vital signs,postoperative recovery with higher quality,and therefore more suitable for brain tumor surgery anesthesia.
