CAJ | 학술논문

目的：分析胱抑素C和β2微球蛋白在2型糖尿病早期肾损害诊断中的意义。方法选择该院2014年1月-2015年1月收治的2型糖尿病患者100例，并选择同期健康体检者80例，对全部入选者的胱抑素C(Cysc)、β2微球蛋白(β2-MG)、尿素(Urea)、肌酐(Crea)进行检测，并对检测结果进行对比分析。结果糖尿病患者的胱抑素C和β2微球蛋白显著高于健康体检者，比较差异有统计学意义(P<0.05)，而且在患者病情发展中胱抑素C和β2微球蛋白水平不断增高。结论在2型糖尿病早期肾损害诊断中，胱抑素C和β2微球蛋白具有非常重要的临床应用价值和参考价值。
목적：분석광억소C화β2미구단백재2형당뇨병조기신손해진단중적의의。방법선택해원2014년1월-2015년1월수치적2형당뇨병환자100례，병선택동기건강체검자80례，대전부입선자적광억소C(Cysc)、β2미구단백(β2-MG)、뇨소(Urea)、기항(Crea)진행검측，병대검측결과진행대비분석。결과당뇨병환자적광억소C화β2미구단백현저고우건강체검자，비교차이유통계학의의(P<0.05)，이차재환자병정발전중광억소C화β2미구단백수평불단증고。결론재2형당뇨병조기신손해진단중，광억소C화β2미구단백구유비상중요적림상응용개치화삼고개치。
Objective To analyze the cystatin C and β2-microglobulin significance in the diagnosis of type 2 diabetes in early nephropathy. Methods Select 100 cases of type 2 diabetes in our hospital from January 2014 to January 2015 were treated and choose healthy 80 cases over the same period, for all the selected candidates of cystatin C, β2-microglobulin, urea, creatinine de-tection , and the test results were analyzed. Results Diabetes cystatin C andβ2-microglobulin was significantly higher than healthy controls, the difference was statistically significant(P<0.05), and in patients with disease progression in cystatin C and β2-mi-croglobulin level continues increased. Conclusion Early diagnosis of diabetic nephropathy in type 2, and cystatin C and β2 mi-croglobulin has very important clinical value and reference value.