医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2015年
17期
2280-2282,2296
,共4页
呼吸机相关性肺炎%痰热壅肺证%痰热清注射液%抗生素%临床肺部感染评分%APACHEⅡ评分%C反应蛋白%降钙素原
呼吸機相關性肺炎%痰熱壅肺證%痰熱清註射液%抗生素%臨床肺部感染評分%APACHEⅡ評分%C反應蛋白%降鈣素原
호흡궤상관성폐염%담열옹폐증%담열청주사액%항생소%림상폐부감염평분%APACHEⅡ평분%C반응단백%강개소원
Ventilator associated pneumonia%Type of TanReYongFei%Tanreqing injection%Antibiotics%Clinic pulmo-nary infection score%APACHEⅡ score%C reactive protein%Procalcitonin
目的：探讨痰热清注射液联合抗生素治疗呼吸机相关性肺炎（VAP）（痰热壅肺证）患者的临床疗效。方法：将96例V A P （痰热壅肺证）患者随机分为实验组（51例）对照组（45例），所有患者均常规使用抗生素及支持对症治疗，实验组患者在此基础上给予痰热清注射液20ml静脉滴注，1次／d ，疗程10d；比较2组患者的临床疗效、临床肺部感染评分（CPIS）、APACHEⅡ评分、机械通气时间、首次脱机成功率及血浆C反应蛋白（CRP）、降钙素原（PCT ）的水平。结果：实验组临床疗效优于对照组（P＜0．05）；2组患者治疗后CPIS、机械通气时间及血浆CRP、PCT水平比较，差异有显著性（P＜0．05），2组患者APACHEⅡ评分和首次脱机成功率比较，差异无显著性（P＞0．05）。治疗中不良反应轻微。结论：痰热清注射液联合抗生素治疗VAP（痰热壅肺证）患者较单纯抗生素治疗的临床疗效更佳。
目的：探討痰熱清註射液聯閤抗生素治療呼吸機相關性肺炎（VAP）（痰熱壅肺證）患者的臨床療效。方法：將96例V A P （痰熱壅肺證）患者隨機分為實驗組（51例）對照組（45例），所有患者均常規使用抗生素及支持對癥治療，實驗組患者在此基礎上給予痰熱清註射液20ml靜脈滴註，1次／d ，療程10d；比較2組患者的臨床療效、臨床肺部感染評分（CPIS）、APACHEⅡ評分、機械通氣時間、首次脫機成功率及血漿C反應蛋白（CRP）、降鈣素原（PCT ）的水平。結果：實驗組臨床療效優于對照組（P＜0．05）；2組患者治療後CPIS、機械通氣時間及血漿CRP、PCT水平比較，差異有顯著性（P＜0．05），2組患者APACHEⅡ評分和首次脫機成功率比較，差異無顯著性（P＞0．05）。治療中不良反應輕微。結論：痰熱清註射液聯閤抗生素治療VAP（痰熱壅肺證）患者較單純抗生素治療的臨床療效更佳。
목적：탐토담열청주사액연합항생소치료호흡궤상관성폐염（VAP）（담열옹폐증）환자적림상료효。방법：장96례V A P （담열옹폐증）환자수궤분위실험조（51례）대조조（45례），소유환자균상규사용항생소급지지대증치료，실험조환자재차기출상급여담열청주사액20ml정맥적주，1차／d ，료정10d；비교2조환자적림상료효、림상폐부감염평분（CPIS）、APACHEⅡ평분、궤계통기시간、수차탈궤성공솔급혈장C반응단백（CRP）、강개소원（PCT ）적수평。결과：실험조림상료효우우대조조（P＜0．05）；2조환자치료후CPIS、궤계통기시간급혈장CRP、PCT수평비교，차이유현저성（P＜0．05），2조환자APACHEⅡ평분화수차탈궤성공솔비교，차이무현저성（P＞0．05）。치료중불량반응경미。결론：담열청주사액연합항생소치료VAP（담열옹폐증）환자교단순항생소치료적림상료효경가。
Objective :To investigate the treatment effects of Tanreqing injection combined with antibiotics for patients with ventilator associated pneumonia(VAP)(type of TanReYongFei) .Methods :96 VAP patients(type of TanReYong‐Fei)were randomly divided into two groups ,experimental group of 51 cases and control group of 45 cases .The cases of control group were treated with antibiotics as well as support therapy .The cases of experimental group were treated with Tanreqing injection (20ml one day) for besides for those therapies as well .The therapy course of both groups was 10 days .The result of these therapies ,clinic pulmonary infection score(CPIS) ,acute physiology and chronic health eval‐uation Ⅱ(APACHEⅡ) score ,days of mechanical ventilation ,the rate of successful weaning for the first time ,serum level of C reaction protein (CRP) and procalcitonin (PCT ) were compared respectively between the two groups .Re‐sults:The efficiency of experimental group was superior to that of control group (P< 0 .05) .There were significantly differences in CPIS ,days of mechanical ventilation ,serum level of CRP and PCT between the two groups (P<0 .05) . There were no significantly differences in APACHE Ⅱ score and he rate of successful weaning for the first time ,be‐tween the two groups (P>0 .05) .The side effect was low in both groups .Conclusion:The treatment effect of Tan‐reqing injection combined with antibiotics for VAP patient (type of TanReYongFei)is better than that of using antibiot‐ics o nly .
