中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
18期
57-58
,共2页
氨甲苯酸注射液%子宫切除术%止血%临床疗效%术中配合
氨甲苯痠註射液%子宮切除術%止血%臨床療效%術中配閤
안갑분산주사액%자궁절제술%지혈%림상료효%술중배합
amino acid injection%hysterectomy%hemostasis%clinical effect%intraoperative cooperation
目的：探讨氨甲苯酸注射液对子宫切除术中出血的临床疗效及术中配合。方法将248例择期行经腹子宫切除患者随机分为对照组和观察组，各124例。两组患者术前均给予缩宫素预防出血，观察组加用氨甲苯酸注射液术中持续滴注。结果观察组患者术中出血量显著小于对照组（ P﹤0.05），而两组患者手术时间无明显差异（ P﹥0.05）；两组患者术后72 h凝血酶原时间( PT )、活化部分凝血活酶时间( APTT )及纤维蛋白原( FIB )等指标均无明显异常，与治疗前相比差异不明显（ P﹥0.05）；术后，观察组患者血红蛋白水平较对照组有所升高，但组间无明显差异（ P﹥0.05）；与对照组相比，观察组患者平均住院时间明显缩短（ P﹤0.05）；两组患者药品不良反应发生率无显著性差异（ P﹥0.05）。结论氨甲苯酸注射液应用于经腹子宫切除术止血治疗过程安全、有效，适宜的术中配合是保证手术顺利进行的重要一环。
目的：探討氨甲苯痠註射液對子宮切除術中齣血的臨床療效及術中配閤。方法將248例擇期行經腹子宮切除患者隨機分為對照組和觀察組，各124例。兩組患者術前均給予縮宮素預防齣血，觀察組加用氨甲苯痠註射液術中持續滴註。結果觀察組患者術中齣血量顯著小于對照組（ P﹤0.05），而兩組患者手術時間無明顯差異（ P﹥0.05）；兩組患者術後72 h凝血酶原時間( PT )、活化部分凝血活酶時間( APTT )及纖維蛋白原( FIB )等指標均無明顯異常，與治療前相比差異不明顯（ P﹥0.05）；術後，觀察組患者血紅蛋白水平較對照組有所升高，但組間無明顯差異（ P﹥0.05）；與對照組相比，觀察組患者平均住院時間明顯縮短（ P﹤0.05）；兩組患者藥品不良反應髮生率無顯著性差異（ P﹥0.05）。結論氨甲苯痠註射液應用于經腹子宮切除術止血治療過程安全、有效，適宜的術中配閤是保證手術順利進行的重要一環。
목적：탐토안갑분산주사액대자궁절제술중출혈적림상료효급술중배합。방법장248례택기행경복자궁절제환자수궤분위대조조화관찰조，각124례。량조환자술전균급여축궁소예방출혈，관찰조가용안갑분산주사액술중지속적주。결과관찰조환자술중출혈량현저소우대조조（ P﹤0.05），이량조환자수술시간무명현차이（ P﹥0.05）；량조환자술후72 h응혈매원시간( PT )、활화부분응혈활매시간( APTT )급섬유단백원( FIB )등지표균무명현이상，여치료전상비차이불명현（ P﹥0.05）；술후，관찰조환자혈홍단백수평교대조조유소승고，단조간무명현차이（ P﹥0.05）；여대조조상비，관찰조환자평균주원시간명현축단（ P﹤0.05）；량조환자약품불량반응발생솔무현저성차이（ P﹥0.05）。결론안갑분산주사액응용우경복자궁절제술지혈치료과정안전、유효，괄의적술중배합시보증수술순리진행적중요일배。
Objective To investigate the clinical effect of amino acid injection used in the hysterectomy and intraoperative cooperation during the operation. Methods Totally 248 patients who were scheduled for accepting transabdominal hysterectomy were randomly divid-ed into the control group and the observation group,124 cases in each group. Before operation,the two groups were given oxytocin to prevent hemorrhage,the observation group was added amino acid injection and continuous infusion during the operation. Results The amount of bleeding in the observation group was significantly less than that in the control group( P ﹤ 0. 05),while the operation time of the two groups had no significantly difference( P ﹥ 0. 05);72 h after operation,the FIB,APTT and PT in the two groups had no significantly difference compared with before treatment( P ﹥ 0. 05);the hemoglobin concentration after operation in the observation group was higher than that in the control group,but the difference had no statistical significance( P ﹥ 0. 05);the average hospitalization time of the observation group was shorter than that of the control group( P ﹤ 0. 05). The occurrence rate of the adverse reactions had no significant difference between the two groups( P ﹥ 0. 05). Conclusion Amino acid injection used in the treatment of hemostasis in pa-tients with abdominal hysterectomy has good safety and effect,and the appropriate intraoperative cooperation can guaranty the smooth op-eration.
