CAJ | 학술논문

目的：分析2～12岁急性中耳炎患儿是否使用抗生素及白细胞计数增高与否与疗效的关系。方法回顾性分析2013年1～12月126例2～12岁急性中耳炎患儿的临床资料，记录其抗生素的使用和白细胞计数，并分别于治疗后1周、1月、3月复查，比较白细胞增高与否及抗生素使用与否的疗效。结果126例患儿中，59．52％（75／126）白细胞计数升高，抗生素总体使用率为73．81％（93／126）。93例随访资料完整的患儿中抗生素使用组74例，观察等待组19例，治疗后一周疗效分别为59．46％（44／74）、52．63％（10／19），治疗后1月分别为75．68％（56／74）、84．21％（16／19），治疗后3月分别为85．14％（63／74）、78．95％（15／19），两组间疗效差异无统计学意义（χ2值分别为0．295、0．903、0．799，均为 P＞0．05），治疗后1、3月的疗效高于1周（ P＜0．05），但治疗后1月与3月的疗效差异无统计学意义（P＞0．05）。抗生素使用组与观察等待组间、白细胞计数增高与不增高组间治疗后1周、1月、3月的疗效差异均无统计学意义（ P＞0．05）。结论2～12岁急性中耳炎患儿的预后与抗生素使用与否、白细胞计数高低无关。
목적：분석2～12세급성중이염환인시부사용항생소급백세포계수증고여부여료효적관계。방법회고성분석2013년1～12월126례2～12세급성중이염환인적림상자료，기록기항생소적사용화백세포계수，병분별우치료후1주、1월、3월복사，비교백세포증고여부급항생소사용여부적료효。결과126례환인중，59．52％（75／126）백세포계수승고，항생소총체사용솔위73．81％（93／126）。93례수방자료완정적환인중항생소사용조74례，관찰등대조19례，치료후일주료효분별위59．46％（44／74）、52．63％（10／19），치료후1월분별위75．68％（56／74）、84．21％（16／19），치료후3월분별위85．14％（63／74）、78．95％（15／19），량조간료효차이무통계학의의（χ2치분별위0．295、0．903、0．799，균위 P＞0．05），치료후1、3월적료효고우1주（ P＜0．05），단치료후1월여3월적료효차이무통계학의의（P＞0．05）。항생소사용조여관찰등대조간、백세포계수증고여불증고조간치료후1주、1월、3월적료효차이균무통계학의의（ P＞0．05）。결론2～12세급성중이염환인적예후여항생소사용여부、백세포계수고저무관。
Objective To study whether the usage of antibiotics and white -blood -cell counts affect the effects of 2~12-year-old children with acute otitis media (AOM ) .Methods A total of 126 children (2~12 years old)with AOM ,from Jan 2013 to Dec 2013 ,were retrospectively analyzed .Usage of antibiotics and white -blood-cell count were recorded at first ,and the relationships between two factors and outcomes of children with AOM were studyed in one week ,one month and three months after treatment ,respectively .Results White blood cell counts were higher than normal in 59 .52% (75/126) 2~12 -year -old children with AOM ,and antibiotics were used in 73 .81% (93 /126) .Ninty three cases were followed -up until 3 month or more .Antibiotics were used in 74 cases ,and watchful waiting were used in the other 19 patients .The effective rates of two groups were 59 .45% and 52 .63% ,75 .68% and 84 .21% ,85 .14% and 78 .95% in one week ,one month and 3 months after treatment ,re‐spectively .There were no statistically significant differences(χ2 values were 0 .295 ,0 .903 ,0 .799 ,P>0 .05) .But the effective rates were signifantly higher in 1 and 3 months than that of in one week (P<0 .05) .There was no sig‐nificant difference (P>0 .05) between one and three months .Whether white-blood-cell count higher than normal or not ,the difference in efficacy was not statistically significant in 1 week ,1 month and 3 months after treatment (P >0 .05) .Conclusion In 2~12-year-old children with acute otitis media (AOM ) ,the final outcomes were inde‐pendent of the usage of antibiotics and white -blood-cell count .