CAJ | 학술논문

目的：探讨6岁以内孤独症儿童听性脑干反应（ABR）特征，评估孤独症儿童的听功能。方法回顾性分析6岁以内听力正常儿童（98例）及孤独症儿童（22例）的ABR测试结果，根据年龄将所有研究对象分为1～2岁组、2＜～3岁组、3＜～6岁组，对各组儿童的ABR反应阈、各波潜伏期及波间期进行统计学分析。结果1～2岁、2＜～3岁及3＜～6岁组正常听力儿童的ABR反应阈平均值分别为15．64±5．02、14．73±4．85及15．57±5．62 dB nHL ，孤独症儿童的ABR反应阈平均值分别为17．50±5．35、17．81±6．58及17．25±6．97 dB nHL ，各年龄组正常听力儿童与孤独症儿童之间ABR平均反应阈值差异无统计学意义（P＞0．05）。在80 dB nHL 短声刺激下，各年龄段孤独症儿童的 ABR各波潜伏期或波间期平均值与正常听力儿童比较，差异均无统计学意义（ P＞0．05）。但是，22例孤独症儿童中，8例（36．36％，8／22）11耳（25．00％，11／44）出现ABR波潜伏期或波间期延长，其中波I、III、V 潜伏期及 I －III、III －V、I －V 波间期延长出现的几率分别为4．55％（2／44）、6．82％（3／44）、13．64％（6／44）、18．18％（8／44）、6．83％（3／44）及15．91％（7／44）。结论部分孤独症儿童存在不同程度的 ABR异常，且表现形式多样，以I－III波间期延长最常见。
목적：탐토6세이내고독증인동은성뇌간반응（ABR）특정，평고고독증인동적은공능。방법회고성분석6세이내은력정상인동（98례）급고독증인동（22례）적ABR측시결과，근거년령장소유연구대상분위1～2세조、2＜～3세조、3＜～6세조，대각조인동적ABR반응역、각파잠복기급파간기진행통계학분석。결과1～2세、2＜～3세급3＜～6세조정상은력인동적ABR반응역평균치분별위15．64±5．02、14．73±4．85급15．57±5．62 dB nHL ，고독증인동적ABR반응역평균치분별위17．50±5．35、17．81±6．58급17．25±6．97 dB nHL ，각년령조정상은력인동여고독증인동지간ABR평균반응역치차이무통계학의의（P＞0．05）。재80 dB nHL 단성자격하，각년령단고독증인동적 ABR각파잠복기혹파간기평균치여정상은력인동비교，차이균무통계학의의（ P＞0．05）。단시，22례고독증인동중，8례（36．36％，8／22）11이（25．00％，11／44）출현ABR파잠복기혹파간기연장，기중파I、III、V 잠복기급 I －III、III －V、I －V 파간기연장출현적궤솔분별위4．55％（2／44）、6．82％（3／44）、13．64％（6／44）、18．18％（8／44）、6．83％（3／44）급15．91％（7／44）。결론부분고독증인동존재불동정도적 ABR이상，차표현형식다양，이I－III파간기연장최상견。
Objective To investigate the characteristics of auditory brainstem response (ABR) in autistic children of 6 years or younger .Methods A total of 98 children with normal hearing and 22 autistic children were en‐rolled in this study .They were divided into 3 groups :1~2 years age group ,2< ~3 years age group ,and 3< ~6 years age group .The thresholds ,wave latencies and interpeak intervals of ABR were statistically analyzed .Results The ABR thresholds in normal hearing children (and autistic children) in 1~2 years age group ,2< ~3 years age group ,and 3< ~6 years age group were 15 .64 ± 5 .02 (17 .50 ± 5 .35) ,14 .73 ± 4 .85 (17 .81 ± 6 .58) ,and 15 .57 ± 5 .62 (17 .25 ± 6 .97) dB nHL ,respectively .There were no significantly statistical difference between the normal hearing children and autistic children (P>0 .05) .In 80 dB nHL click sound stimulus ,there was also no statistical difference in the values of peak latencies or interpeak intervals of ABR between normal hearing children and autistic children (P> 0 .05) ,whereas ,prolongation of peak latencies or interpeak intervals of ABR occurred in 36 .36%(25 .00% ears) autistic children .The ratio of prolongation of peak latencies of I ,III ,V waves and interpeak inter‐vals of I-III ,III-V ,I-V occurred in 4 .54% ,6 .82% ,13 .64% ,18 .18% ,6 .83% and 15 .91% ,respectively . Conclusion The ABR in some autistic children present abnormality and occur in various forms with the prolongation of interpeak intervals of I -III as the most common .