CAJ | 학술논문

目的：对比在常规治疗基础上加用阿托伐他汀与曲美他嗪治疗不稳定型心绞痛的效果。方法：选取2013年3月－2014年3月我院收治的不稳定型心绞痛患者72例作为研究对象，并将患者按数字随机表法分为阿托伐他汀组和曲美他嗪组，每组36例。阿托伐他汀组行常规抗心绞痛药物治疗同时加用阿托伐他汀。曲美他嗪组行常规抗心绞痛药物治疗同时加用曲美他嗪。1个疗程后，将两组患者的心绞痛每周平均发作次数、心绞痛单次持续发作平均时间、TC、LDL‐C、HDL‐C、TG、CRP指标进行对比分析。结果：曲美他嗪组患者总有效率94．4％，阿托伐他汀组为77.8％，两组差异显著，有统计学意义（P＜0．05）。曲美他嗪组患者心绞痛单次持续发作平均时间及CRP指标明显优于阿托伐他汀组患者，两组差异显著，有统计学意义（P＜0．05）。结论：曲美他嗪相对阿托伐他汀治疗不稳定型心绞痛的效果更好，能够有效改善不稳定型心绞痛患者临床症状，值得在临床进一步推广。
목적：대비재상규치료기출상가용아탁벌타정여곡미타진치료불은정형심교통적효과。방법：선취2013년3월－2014년3월아원수치적불은정형심교통환자72례작위연구대상，병장환자안수자수궤표법분위아탁벌타정조화곡미타진조，매조36례。아탁벌타정조행상규항심교통약물치료동시가용아탁벌타정。곡미타진조행상규항심교통약물치료동시가용곡미타진。1개료정후，장량조환자적심교통매주평균발작차수、심교통단차지속발작평균시간、TC、LDL‐C、HDL‐C、TG、CRP지표진행대비분석。결과：곡미타진조환자총유효솔94．4％，아탁벌타정조위77.8％，량조차이현저，유통계학의의（P＜0．05）。곡미타진조환자심교통단차지속발작평균시간급CRP지표명현우우아탁벌타정조환자，량조차이현저，유통계학의의（P＜0．05）。결론：곡미타진상대아탁벌타정치료불은정형심교통적효과경호，능구유효개선불은정형심교통환자림상증상，치득재림상진일보추엄。
Objective :To Compare the effect of atorvastatin and trimetazidine in the treatment of unstable angina pec‐toris on the basis of routine treatment .Methods :72 patients with unstable angina pectoris in our hospital from March 2013 to March 2014 were selected which as the research subject according to the random number table method ,the pa‐tients were divided into atorvastatin group and trimetazidine group ,36 cases in each group .Atorvastatin group treated with conventional anti angina drug therapy combined with atorvastatin .Trimetazidine group was given conventional an‐ti angina drug therapy combined with trimetazidine .After a course of treatment ,the two groups of patients with angi‐na pectoris daily average number of episodes ,angina pectoris single continued seizure average time ,TC ,LDL‐C ,HDL‐C ,TG and CRP were compared and analyzed .Results:Trimetazidine group total effective rate was 94 .4% ,atorvastatin group total effective rate was 77 .8% ,two groups of the total efficiency of significant differences (P<0 .05) and was statistically significant .Trimetazidine hydrochloride group in patients with angina pectoris single sustained attack aver‐age time and CRP significantly better than atorvastatin in atorvastatin group patients ,there was significant difference between two groups (P<0 .05) ,statistically significance .Conclusion:Compared with atorvastatin ,trimetazidine in the treatment of unstable angina pectoris had better effect ,which can effectively improve the Clinical symptoms of unstable angina pectoris ,it is worth further promotion in clinical .