CAJ | 학술논문

目的：分析婴幼儿泪囊炎患者的主要致病菌和药物敏感性,为临床合理用药提供依据。 　　方法：采集83例86眼婴幼儿泪囊炎患者的泪囊分泌物进行细菌培养和药敏试验分析。 　　结果：患者86眼中,84眼细菌培养阳性,阳性率为97.7%,共分离出细菌94株,其中革兰氏阳性菌67株,占71.3%,革兰氏阳性菌的前三位敏感药物为利福平、左氧氟沙星、氯霉素；革兰氏阴性菌27株,占28.7%,革兰氏阴性菌前三位敏感药物为左氧氟沙星、氯霉素、夫西地酸、头孢他啶。 　　结论：G+菌为婴幼儿泪囊炎的优势致病菌,其中以草绿色链球菌和表皮葡萄球菌最常见。 G+菌较G-菌耐药性高,左氧氟沙星、氯霉素等治疗婴幼儿泪囊炎有效。
목적：분석영유인루낭염환자적주요치병균화약물민감성,위림상합리용약제공의거。 　　방법：채집83례86안영유인루낭염환자적루낭분비물진행세균배양화약민시험분석。 　　결과：환자86안중,84안세균배양양성,양성솔위97.7%,공분리출세균94주,기중혁란씨양성균67주,점71.3%,혁란씨양성균적전삼위민감약물위리복평、좌양불사성、록매소；혁란씨음성균27주,점28.7%,혁란씨음성균전삼위민감약물위좌양불사성、록매소、부서지산、두포타정。 　　결론：G+균위영유인루낭염적우세치병균,기중이초록색련구균화표피포도구균최상견。 G+균교G-균내약성고,좌양불사성、록매소등치료영유인루낭염유효。
AIM: To analyze the pathogenic bacteria and drug sensitivity on infants with dacryocystitis and provide the basis for the rational drug use. METHODS: Lacrimal sac secretions from 83 infants ( 86 eyes ) with dacryocystitis were used to do bacterial cultures and drug sensitivity tests. RESULTS:In all 86 eyes, specimens of 84 eyes were positive in bacterial culture, and the pathogenic bacteria positive rate was 97. 7%. Totally 94 bacterial strains were isolated from lacrimal sac secretions. The positive rates of gram-positive bacteria were 71. 3% (67 strains) and gram-positive bacteria were sensitive to rifampicin, levofloxacin and chloramphenicol. The positive rates of gram-negative bacteria were 28. 7% (27 strains), and gram-negative bacteria were sensitive to levofloxacin, chloramphenicol, fusidic acid and ceftazidime. CONCLUSION: Gram - positive bacteria are the preponderant pathogenic bacteria of dacryocystitis in infants, and the most common of which are streptococcus viridans and staphylococcus epidermidis. The results of drug sensitivity tests show that drug resistance rate of gram-positive bacteria are higher than that of gram-negative bacteria. Levofloxacin and chloramphenicol are effective to infants with dacryocystitis.