国际眼科杂志
國際眼科雜誌
국제안과잡지
International Eye Science
2015年
9期
1603-1605
,共3页
何旭亭%王大龙%张宏%贺海宁
何旭亭%王大龍%張宏%賀海寧
하욱정%왕대룡%장굉%하해저
康柏西普%玻璃体腔注射%湿性年龄相关性黄斑变性%曲安奈德
康柏西普%玻璃體腔註射%濕性年齡相關性黃斑變性%麯安奈德
강백서보%파리체강주사%습성년령상관성황반변성%곡안내덕
Conbercept%intravitreal injection%wet age-related macular degeneration%triamcinolone acetonide
目的：观察康柏西普玻璃体腔注射治疗湿性年龄相关性黄斑变性的临床疗效。<br> 方法：将确诊的60例湿性年龄相关性黄斑变性的患者,根据随机数字表法分为治疗组和对照组各30例。治疗组注射康柏西普0.05mL,对照组注射曲安奈德0.1mL。在治疗前及治疗后1d,1、3mo采用标准视力表对患者进行最佳矫正视力( BCVA)检查；用光学相干断层扫描仪( OCT)检测黄斑中心凹视网膜厚度。并观察患者治疗后1d,1、3 mo内出现的并发症情况,包括前房炎性反应、角膜水肿、高眼压等。<br> 结果：治疗组治疗后1d,1、3mo视力提高明显好于对照组(P<0.05)。治疗组治疗后1d,1、3mo的黄斑中心凹视网膜厚度明显低于对照组(P<0.05)。治疗组和对照组治疗后1d,1、3mo均未出现眼部严重并发症。<br> 结论：康柏西普玻璃体腔注射治疗湿性年龄相关性黄斑变性可以提高疗效。
目的：觀察康柏西普玻璃體腔註射治療濕性年齡相關性黃斑變性的臨床療效。<br> 方法：將確診的60例濕性年齡相關性黃斑變性的患者,根據隨機數字錶法分為治療組和對照組各30例。治療組註射康柏西普0.05mL,對照組註射麯安奈德0.1mL。在治療前及治療後1d,1、3mo採用標準視力錶對患者進行最佳矯正視力( BCVA)檢查；用光學相榦斷層掃描儀( OCT)檢測黃斑中心凹視網膜厚度。併觀察患者治療後1d,1、3 mo內齣現的併髮癥情況,包括前房炎性反應、角膜水腫、高眼壓等。<br> 結果：治療組治療後1d,1、3mo視力提高明顯好于對照組(P<0.05)。治療組治療後1d,1、3mo的黃斑中心凹視網膜厚度明顯低于對照組(P<0.05)。治療組和對照組治療後1d,1、3mo均未齣現眼部嚴重併髮癥。<br> 結論：康柏西普玻璃體腔註射治療濕性年齡相關性黃斑變性可以提高療效。
목적：관찰강백서보파리체강주사치료습성년령상관성황반변성적림상료효。<br> 방법：장학진적60례습성년령상관성황반변성적환자,근거수궤수자표법분위치료조화대조조각30례。치료조주사강백서보0.05mL,대조조주사곡안내덕0.1mL。재치료전급치료후1d,1、3mo채용표준시력표대환자진행최가교정시력( BCVA)검사；용광학상간단층소묘의( OCT)검측황반중심요시망막후도。병관찰환자치료후1d,1、3 mo내출현적병발증정황,포괄전방염성반응、각막수종、고안압등。<br> 결과：치료조치료후1d,1、3mo시력제고명현호우대조조(P<0.05)。치료조치료후1d,1、3mo적황반중심요시망막후도명현저우대조조(P<0.05)。치료조화대조조치료후1d,1、3mo균미출현안부엄중병발증。<br> 결론：강백서보파리체강주사치료습성년령상관성황반변성가이제고료효。
AIM: To observe the clinical curative effect of conbercept intravitreal injection for the treatment of wet age-related macular degeneration. <br> METHODS:Sixty patients with wet age related macular degeneration were randomly divided into treatment group 30 cases and control group 30 cases according to the random number table. The treatment group was injected with Conbercept 0. 05mL, the control group was injected with triamcinolone acetonide 0. 1mL. The best corrected visual acuity (BCVA) was performed before and after 1d, 1 and 3mo after treatment, and the thickness of macular was detected by optical coherence tomography ( OCT ) . The complications of patients were observed after 1d, 1 and 3mo, including inflammatory reaction, corneal edema, anterior chamber, high intraocular pressure, etc.RESULTS:In treatment group 1d, 1 and 3mo after treatment, eyesight was improved significantly better than the control group (P<0. 05), macular center concave retinal thickness was significantly lower than the control group (P<0. 05). Treatment group and control group 1d, 1 and 3mo after treatment did not appear serious eye complications. <br> CONCLUSION:Intravitreal injection of Conbercept in the treatment of wet age-related macular degeneration can improve the curative effect.
