CAJ | 학술논문

目的：探究对急性缺血性脑血管病患者行氯吡格雷与吲哚布芬片疗法的临床效果。方法整群选取2013年5月-2015年5月该院接收的急性缺血性脑血管病患者76例为该研究对象，±据分层法将其划分为对照组、实验组，分别行氯吡格雷治疗、吲哚布芬片治疗，对比疗效。结果实验组行吲哚布芬片治疗后有效率（97.37%vs 94.74%)较对照组无明显改变，且血小板聚集率（0.5浓度诱导：（23.90±3.55） vs（23.28±2.02）；1.0浓度诱导：（47.35±3.34）vs （47.01±2.25））较对照组无显著性变化，差异无统计学意义（P>0.05）。结论对急性缺血性脑血管病患者行吲哚布芬片或氯吡格雷治疗，均可发挥抗血小板聚集作用，减少血小板聚集率，临床须引起足够重视。
목적：탐구대급성결혈성뇌혈관병환자행록필격뢰여신타포분편요법적림상효과。방법정군선취2013년5월-2015년5월해원접수적급성결혈성뇌혈관병환자76례위해연구대상，±거분층법장기화분위대조조、실험조，분별행록필격뢰치료、신타포분편치료，대비료효。결과실험조행신타포분편치료후유효솔（97.37%vs 94.74%)교대조조무명현개변，차혈소판취집솔（0.5농도유도：（23.90±3.55） vs（23.28±2.02）；1.0농도유도：（47.35±3.34）vs （47.01±2.25））교대조조무현저성변화，차이무통계학의의（P>0.05）。결론대급성결혈성뇌혈관병환자행신타포분편혹록필격뢰치료，균가발휘항혈소판취집작용，감소혈소판취집솔，림상수인기족구중시。
Objective To explore the clinical effect of indobufen tablets and clopidogrel in the treatment of patients with acute ischemic cerebrovascular disease. Methods 76 patients with acute ischemic cerebrovascular disease admitted into the hospital from May 2013 to May 2015 were selected as the research object and were divided into the control group and the experimental group according to stratification method. And the two groups were respectively treated with clopidogrel and indobufen tablets. The curative effects were compared. Results The efficiency of the experimental group after the given treatment was (97.37% vs 94.74%). Compared with that of the control group, there were no obvious changes. And the rate of platelet aggregation (0.5 concentration induction: (23.90±355) vs (23.28±2.02); 1.0 concentration induction: (47.35±3.34) vs. (47.01±2.25) did not change significantly compared with those of the control group and the difference was not significant (P > 0.05). Conclusion To adopt indobufen tablets or clopidogrel in the treatment of acute ischemic cerebrovascular disease both can inhibit platelet aggregation and reduce the rate of platelet aggregation, so enough clinical attention should be paid.