CAJ | 학술논문

随着干细胞科学的飞速发展,近年间充质干细胞( MSCs)的研究已成为热点。骨髓间充质干细胞( BMSCs)是来源于骨髓中的MSCs,具有免疫原性低、有多向分化潜能、促进损伤修复、性能稳定等生物学优点。研究发现, BMSCs是医学领域中极具前景的一种特殊细胞,几乎在各系统疾病的治疗方面都有广泛应用。眼科学者的研究也发现, BMSCs已经成为角膜疾病中一种兼具科研价值和临床价值的种子细胞,为角膜盲患者的康复带来了一线希望。本文就BMSCs对角膜损伤与角膜移植排斥反应治疗方面的研究做一综述。
수착간세포과학적비속발전,근년간충질간세포( MSCs)적연구이성위열점。골수간충질간세포( BMSCs)시래원우골수중적MSCs,구유면역원성저、유다향분화잠능、촉진손상수복、성능은정등생물학우점。연구발현, BMSCs시의학영역중겁구전경적일충특수세포,궤호재각계통질병적치료방면도유엄범응용。안과학자적연구야발현, BMSCs이경성위각막질병중일충겸구과연개치화림상개치적충자세포,위각막맹환자적강복대래료일선희망。본문취BMSCs대각막손상여각막이식배척반응치료방면적연구주일종술。
In recent years, with the rapid development of stem cells science, mesenchymal stem cells ( MSCs ) have become a research hotspot. Bone marrow mesenchymal stem cells ( BMSCs ) are MSCs that derived from bone marrow with some advantages, such as the potential of multi- directional differentiation, low immunogenicity, promoting damage repair and stable performance. The study by many scholars found that BMSCs are promising special cells in the field of medicine, and BMSCs have been widely used in almost every system in treatment of disease. For treatment of corneal disease, ophthalmology scholars found that BMSCs have already become a kind of seed cells with clinical and science value. BMSCs brought promising to the patients who have complex corneal disease. In this paper, we introduce the function of BMSCs on the treatment of corneal injury and corneal allograft rejection.