CAJ | 학술논문

利用核磁滴定法研究了极性链状二肽(均为LL构型)与金属离子之间的相互作用。极性二肽在与一价金属离子相互作用时,两者间的化学计量比为1∶1,并求得Li+与10种极性二肽结合常数的大小,其中与L-Glu-L-Glu的结合常数最大,这可能与L-Glu-L-Glu含有较多的富电子原子有关。在此基础上又研究了Cu2+,Zn2+,Co2+3种二价金属离子与极性二肽间的相互作用,结果表明,二价金属离子与二肽间的相互作用是通过两步完成的。
이용핵자적정법연구료겁성련상이태(균위LL구형)여금속리자지간적상호작용。겁성이태재여일개금속리자상호작용시,량자간적화학계량비위1∶1,병구득Li+여10충겁성이태결합상수적대소,기중여L-Glu-L-Glu적결합상수최대,저가능여L-Glu-L-Glu함유교다적부전자원자유관。재차기출상우연구료Cu2+,Zn2+,Co2+3충이개금속리자여겁성이태간적상호작용,결과표명,이개금속리자여이태간적상호작용시통과량보완성적。
The interactions of 10 polar chain dipeptides( L-L configuration) with metal ions were exam-ined by NMR. These polar chain dipeptides exhibited a tremendous selectivity toward monovalent mental ion, showing a stoichiometric binding with 1∶1, and the association constants of dipeptides with Li+ were acquired. The results showed that L-Glu-L-Glu had stronger binding ability toward Li+ ions than other dipeptides, and suggested the electron-rich atoms in L-Glu-L-Glu molecular were favorable for the inter-action with metal ions. Furthermore, the interactions of divalent metal ions( Cu2+, Zn2+, Co2+) with 10 polar chain dipetieds were studied, which implied the interaction between them was carried out in two stages.