中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
17期
79-80,81
,共3页
酚磺乙胺%子宫肌瘤%子宫切除术%临床疗效
酚磺乙胺%子宮肌瘤%子宮切除術%臨床療效
분광을알%자궁기류%자궁절제술%림상료효
etamsylate injection%myomectomy%hysterectomy%clinical efficacy
目的：探讨酚磺乙胺注射液用于子宫切除术减少术后出血的疗效及最佳下床活动时间。方法选取医院收治的子宫肌瘤患者120例，均行腹腔镜辅助阴式子宫切除术（LAVH）治疗，术前给予酚磺乙胺注射液（术前15～30 min静脉滴注0.25～0.5 g）。并根据下床活动时间的不同，随机分为A组、B组、C组，各40例。A组术后24 h内下床活动，B组术后25～48 h下床活动，C组术后48～72 h下床活动。结果120例患者手术用时（102.2±17.5）min；术中出血量为（102.63±11.54）mL，术后2 h出血量为（55.32±10.32）mL，术后2～24 h出血量为（67.56±18.67）mL，术后24 h总出血量（109.36±19.84）mL。所有患者术中血压平稳，无不良事件发生；术后均无血管栓塞发生。与B组及C组相比，A组术后肛门排气时间提前( P＜0.05)，发热天数、住院天数均缩短( P＜0.05)。3组术后阴道断端出血情况与疼痛程度比较无显著性差异（ P＞0.05）。结论对于行LAVH的子宫肌瘤患者，术前应用酚磺乙胺药物，可有效缩短手术时间，控制术中、术后出血量，减少不良事件发生率。子宫切除术后24 h内下床活动可有效促进肛门排气，缩短术后发热及住院天数。
目的：探討酚磺乙胺註射液用于子宮切除術減少術後齣血的療效及最佳下床活動時間。方法選取醫院收治的子宮肌瘤患者120例，均行腹腔鏡輔助陰式子宮切除術（LAVH）治療，術前給予酚磺乙胺註射液（術前15～30 min靜脈滴註0.25～0.5 g）。併根據下床活動時間的不同，隨機分為A組、B組、C組，各40例。A組術後24 h內下床活動，B組術後25～48 h下床活動，C組術後48～72 h下床活動。結果120例患者手術用時（102.2±17.5）min；術中齣血量為（102.63±11.54）mL，術後2 h齣血量為（55.32±10.32）mL，術後2～24 h齣血量為（67.56±18.67）mL，術後24 h總齣血量（109.36±19.84）mL。所有患者術中血壓平穩，無不良事件髮生；術後均無血管栓塞髮生。與B組及C組相比，A組術後肛門排氣時間提前( P＜0.05)，髮熱天數、住院天數均縮短( P＜0.05)。3組術後陰道斷耑齣血情況與疼痛程度比較無顯著性差異（ P＞0.05）。結論對于行LAVH的子宮肌瘤患者，術前應用酚磺乙胺藥物，可有效縮短手術時間，控製術中、術後齣血量，減少不良事件髮生率。子宮切除術後24 h內下床活動可有效促進肛門排氣，縮短術後髮熱及住院天數。
목적：탐토분광을알주사액용우자궁절제술감소술후출혈적료효급최가하상활동시간。방법선취의원수치적자궁기류환자120례，균행복강경보조음식자궁절제술（LAVH）치료，술전급여분광을알주사액（술전15～30 min정맥적주0.25～0.5 g）。병근거하상활동시간적불동，수궤분위A조、B조、C조，각40례。A조술후24 h내하상활동，B조술후25～48 h하상활동，C조술후48～72 h하상활동。결과120례환자수술용시（102.2±17.5）min；술중출혈량위（102.63±11.54）mL，술후2 h출혈량위（55.32±10.32）mL，술후2～24 h출혈량위（67.56±18.67）mL，술후24 h총출혈량（109.36±19.84）mL。소유환자술중혈압평은，무불량사건발생；술후균무혈관전새발생。여B조급C조상비，A조술후항문배기시간제전( P＜0.05)，발열천수、주원천수균축단( P＜0.05)。3조술후음도단단출혈정황여동통정도비교무현저성차이（ P＞0.05）。결론대우행LAVH적자궁기류환자，술전응용분광을알약물，가유효축단수술시간，공제술중、술후출혈량，감소불량사건발생솔。자궁절제술후24 h내하상활동가유효촉진항문배기，축단술후발열급주원천수。
Objective To investigate the curative effect of etamsylate injection in reducing bleeding after hysterectomy and PostoPerative best bed activity time. Methods 120 Patients with uterine fibroids were selected,all Patients were Performed laParoscoPic assisted vaginal hysterectomy ( LAVH ) ,and given etamsylate injection PreoPerative ( PreoPerative 15-30 minutes by intravenous driP or intramuscular injection of 0. 25-0. 5 g ) . The Patients were randomly divided into grouP A, grouP B and grouP C according to the different bed activity time,40 cases in each grouP. GrouP A made off-bed activity within 24 h after oPeration,grouP B 25-48 h and grouP C,48-72 h. Results The oPeration time of the 120 Patient was ( 102. 2 ± 17. 5 ) min; intraoPeratie blood loss was ( 102. 63 ± 11. 54 ) mL,( 55. 32 ± 10. 32 ) mL after 2 h,( 67. 56 ± 18. 67 ) mL after 2-24 h,the total blood loss after 24 h was ( 109. 36 ± 19. 84 ) mL. The intraoPerative blood Pressure of all Patient was stable,with no adverse events; no PostoPerative vascular embolization occured. ComPared with grouP B,and grouP C,PostoPerative anal exhaust time was advanced in grouP A ( P < 0. 05 ) ,the fever days,hosPitalization days were short-ened in grouP A ( P < 0. 05 ) ,the difference is significant. The vaginal bleeding and Pain of incision had no difference in the 3 grouPs ( P > 0. 05 ) . Conclusions For Patients with uterine fibroids LAVH,the PreoPerative use of etamsylat drugs can short oPeration time, control oPeratine and PostoPerative vaginal haemorrhage amount,reduce the incidence of adverse reactions, the best PostoPerative bed time is within 24 h,which can Promote the anus exhaust shorten fever days and hosPitalization days.
