CAJ | 학술논문

目的：观察逍遥丸联合生脉注射液对乳腺癌患者围手术期应激反应的影响。方法将60例患者随机分为观察组和对照组，各30例。对照组给予常规护理和心理疏导，观察组在此基础上给予逍遥丸口服及生脉注射液静脉滴注治疗，术前1 d至术后7 d为治疗周期。结果治疗后同期比较，观察组患者术后3 d的体温、收缩压（SBP）和心率（HR）水平优于对照组（ P＜0.05）。术后3 d观察组患者血常规指标中的白细胞计数（WBC）、中性粒细胞计数（ANC）、红细胞压积（Hct）和血小板计数（PLT）水平以及术后7 d所有指标水平均优于对照组（ P＜0.05）。术后7 d，观察组患者血常规各指标水平均恢复至术前水平。术后3 d起，观察组患者的血清C反应蛋白、白细胞介素－6和肿瘤坏死因子－α水平均显著低于对照组（ P＜0.05）。结论逍遥丸联合生脉注射液可有效降低乳腺癌患者围手术期的应激反应，提高患者免疫功能，对促进术后恢复有积极作用。
목적：관찰소요환연합생맥주사액대유선암환자위수술기응격반응적영향。방법장60례환자수궤분위관찰조화대조조，각30례。대조조급여상규호리화심리소도，관찰조재차기출상급여소요환구복급생맥주사액정맥적주치료，술전1 d지술후7 d위치료주기。결과치료후동기비교，관찰조환자술후3 d적체온、수축압（SBP）화심솔（HR）수평우우대조조（ P＜0.05）。술후3 d관찰조환자혈상규지표중적백세포계수（WBC）、중성립세포계수（ANC）、홍세포압적（Hct）화혈소판계수（PLT）수평이급술후7 d소유지표수평균우우대조조（ P＜0.05）。술후7 d，관찰조환자혈상규각지표수평균회복지술전수평。술후3 d기，관찰조환자적혈청C반응단백、백세포개소－6화종류배사인자－α수평균현저저우대조조（ P＜0.05）。결론소요환연합생맥주사액가유효강저유선암환자위수술기적응격반응，제고환자면역공능，대촉진술후회복유적겁작용。
Absract:Objective To observe the influence of Xiaoyao Pill combined with Shengmai Injection on stress resPonse of breast cancer Pa-tients in Peri oPeration Period. Methods 60 cases of breast cancer Patients were randomly divided into the observation grouP and the control grouP,30 cases in each grouP. Routine nursing and Psychological counseling was Prescribed in the control grouP. On the basis of control grouP,Xiaoyao Pill was Prescribed for oral,and Shengmai injection was Prescribed for intravenous driP in the observation the grouP. The treatment Period started from PreoPerative 1 d to PostoPerative 7 d. Results At the same time Points after treatment,the temPerature and levels of SBP and HR in the observation grouP were better than those in the control grouP ( P < 0. 05 ) in third days after surgery. For blood routine index, the levels of WBC,ANC,HCT and PLT in the third day after surgery, and all the index seven days after surgery in the observation grouP were better than those in the control grouP ( P < 0. 05 ) . Seven days after surgery,the levels of all the index of blood routine index recovered to the PreoPerative level. Since the third day after oPeration,the levels of CRP,IL-6, TNF-α in the observation grouP were significantly lower than those of the control grouP ( P < 0. 05 ) . Conclusion Xiaoyao Pill com-bined with Shengmai Injection can effectively reduce the stress resPonse in breast cancer Patients during the Peri oPeration,imProve the immune function,and have a Positive role in Promoting PostoPerative recovery.