广州化工
廣州化工
엄주화공
Guangzhou Chemical Industry
2015年
17期
47-48
,共2页
张丹%刘坤%冯忠建%赵春深
張丹%劉坤%馮忠建%趙春深
장단%류곤%풍충건%조춘심
芳基硼酸%4-(2-(二乙胺基)乙基)苯基硼酸%合成
芳基硼痠%4-(2-(二乙胺基)乙基)苯基硼痠%閤成
방기붕산%4-(2-(이을알기)을기)분기붕산%합성
aryl boric acid%4-(2-( diethylaMino) ethyl) phenylboronic acid%synthesis
芳基硼酸类化合物具有低毒性,良好的热稳定性,官能团兼容性及对水、空气不敏感等优点。4-(2-(二乙胺基)乙基)苯基硼酸作为一种重要的中间体,在有机合成中的应用相当广泛。以对溴苯乙酸为原料,经还原、酰化、水解三步反应,合成目标化合物,并经过1 H NMR进行结构表征。目标化合物作为市场一种新的化合物,有很好的研究前景。
芳基硼痠類化閤物具有低毒性,良好的熱穩定性,官能糰兼容性及對水、空氣不敏感等優點。4-(2-(二乙胺基)乙基)苯基硼痠作為一種重要的中間體,在有機閤成中的應用相噹廣汎。以對溴苯乙痠為原料,經還原、酰化、水解三步反應,閤成目標化閤物,併經過1 H NMR進行結構錶徵。目標化閤物作為市場一種新的化閤物,有很好的研究前景。
방기붕산류화합물구유저독성,량호적열은정성,관능단겸용성급대수、공기불민감등우점。4-(2-(이을알기)을기)분기붕산작위일충중요적중간체,재유궤합성중적응용상당엄범。이대추분을산위원료,경환원、선화、수해삼보반응,합성목표화합물,병경과1 H NMR진행결구표정。목표화합물작위시장일충신적화합물,유흔호적연구전경。
Compounds of arylboronic acid have the advance of low toxicity, good thermal stability, compatibility and functional groups on water, air insensitivity, and so on. 4-(2-( diethylamino) ethyl) phenyl acid is quite important as an important intermediate in organic synthesis. The target compound was synthesized after reduction, acylation, hydrolysis three-step reaction with the 4-bromophenylacwtic acid as the lead compound, and its structure was tested by 1 H NMR. As a new compound in the market, there are good prospects for the study.