CAJ | 학술논문

目的：观察小儿消积止咳口服液联合阿奇霉素治疗支原体肺炎的临床疗效及其对患儿体液免疫功能的影响。方法将120例小儿支原体肺炎患儿分为对照组和观察组，各60例。两组患儿均给予阿奇霉素治疗，观察组患儿加服小儿消积止咳口服液。对所有患儿均进行IgA，IgM及补体C3和C4水平检测，比较两组患儿细胞和体液免疫功能的差异。结果观察组总有效率为96.67%，明显高于对照组的70.00%（ P﹤0.05）；治疗后，观察组患儿的IgA和IgM分别为（0.88±0.36）g/L和（1.21±0.39）g/L，明显低于对照组患儿的（1.69±0.54）g/L和（1.99±0.51）g/L（ P﹤0.05）；两组患儿补体C3和C4治疗前后比较，差异无统计学意义( P﹥0.05)。结论阿奇霉素联合小儿消积止咳口服液治疗支原体肺炎可显著提高临床疗效，降低体液免疫反应，促进患儿康复，值得临床推广。
목적：관찰소인소적지해구복액연합아기매소치료지원체폐염적림상료효급기대환인체액면역공능적영향。방법장120례소인지원체폐염환인분위대조조화관찰조，각60례。량조환인균급여아기매소치료，관찰조환인가복소인소적지해구복액。대소유환인균진행IgA，IgM급보체C3화C4수평검측，비교량조환인세포화체액면역공능적차이。결과관찰조총유효솔위96.67%，명현고우대조조적70.00%（ P﹤0.05）；치료후，관찰조환인적IgA화IgM분별위（0.88±0.36）g/L화（1.21±0.39）g/L，명현저우대조조환인적（1.69±0.54）g/L화（1.99±0.51）g/L（ P﹤0.05）；량조환인보체C3화C4치료전후비교，차이무통계학의의( P﹥0.05)。결론아기매소연합소인소적지해구복액치료지원체폐염가현저제고림상료효，강저체액면역반응，촉진환인강복，치득림상추엄。
Objective To observe the clinical effect of Xiaoerxiaojizhike Oral Liquid combined with azithromycin for treating mycoplasma pneumonia and its effect on humoral immune function. Methods Totally 120 children patients with mycoplasma pneumonia were divided into the control group and the observation group,60 cases in each group. The control group was given azithromycin,on this basis the observation group was given Xiaoerxiaojizhike Oral Liquid. The IgA,IgM and C3,C4 levels of the children patients were detected,the dif-ferences of cellular and humoral immune function were compared between the two group. Results The total effective rate in the observation group was 96. 67%,which was significantly higher than 70. 00% in the control group( P ﹤ 0. 05 );after treat ment ,the IgA and IgM was(0. 88 ± 0. 36)g/L and (1. 21 ± 0. 39)g/L respectively in the observation group,which was significantly lower than (1. 69 ± 0. 54)g/L,(1. 99 ± 0. 51)g/L in the control group( P ﹤ 0. 05). The C3 and C4 in the two groups had no significantly differ-ence before and after treatment( P ﹥ 0. 05). Conclusion Xiaoerxiaojizhike Oral Liquid combined with azithromycin in treating mycoplas-ma pneumonia can significantly improve the clinical efficacy,reducing the humoral immune response,promote rehabilitation of children, and is worth of clinical promotion.