疑难病杂志
疑難病雜誌
의난병잡지
Chinese Journal of Difficult and Complicated Cases
2015年
10期
1059-1063
,共5页
武建军%董隽%曾强%英明中
武建軍%董雋%曾彊%英明中
무건군%동준%증강%영명중
嗜酸细胞性膀胱炎%病因%流行病学%诊断%治疗
嗜痠細胞性膀胱炎%病因%流行病學%診斷%治療
기산세포성방광염%병인%류행병학%진단%치료
Eosinophilic cystitis%Etiology%Epidemiology%Diagnosis%Therapy
目的:分析国人嗜酸细胞性膀胱炎临床特点,探索临床诊断及治疗原则。方法报告1例嗜酸细胞性膀胱炎,并回顾性分析1986年1月—2014年12月嗜酸细胞性膀胱炎患者179例文献报道。结果嗜酸细胞性膀胱炎患者均经膀胱镜检查、活检后经病理明确诊断。男119例,女61例,年龄0 fl.8~78(38.5±18.5)岁,常见症状有肉眼或镜下血尿(68.89%)以及尿频、尿急和尿痛(46.67%),其他症状还包括耻骨上疼痛(30.56%)、排尿困难(30.00%)、腰痛(7.18%)、尿潴留(2.78%)等。绝大多数患者无异常体征(86.11%),部分患者可有耻骨上压痛(10.56%),下腹部包块(3.33%)和肾区叩击痛(3.33%)。影像学检查异常阳性率依次是CT扫描93.50%(115/123)、膀胱B型超声91.39%(138/151)和静脉肾盂造影(IUV)77.65%(66/85)。膀胱镜检查病变呈多处和广泛弥漫性病变76例(44.71%),累及膀胱三角区23例(13.53%),左、右或双侧输尿管开口24例(14.12%),右侧壁22例(12.94%),后壁19例(11.18%),膀胱底部13例(7.65%),左侧壁和膀胱顶部各9例(5.29%),前壁和膀胱颈均为6例(3.53%)。并发肾积水37例(20.55%),膀胱容量明显缩小、膀胱充盈困难或无法充盈19例(10.55%),尿潴留10例(5.56%),膀胱结石2例(1.11%),肿物表面沙粒样钙化和膀胱颈硬化症各1例(0.56%)。确诊后单纯内科治疗59例(32.78%),膀胱部分切除31例(17.22%),膀胱部分切除+内科治疗25例(13.89%),膀胱镜治疗+内科治疗23例(12.78%),单纯膀胱镜治疗18例(10.00%),膀胱全切和膀胱自体扩大术各1例(0.56%),余22例(12.22%)未详述内科治疗。本组病例中治愈156例(86.67%)。结论嗜酸细胞性膀胱炎可发于各年龄段,男性多于女性。常见症状包括血尿,尿频、尿急、尿痛,和耻骨上疼痛,排尿困难等。经尿道切除膀胱病变,结合皮质激素、抗过敏等综合治疗,多数患者预后良好。
目的:分析國人嗜痠細胞性膀胱炎臨床特點,探索臨床診斷及治療原則。方法報告1例嗜痠細胞性膀胱炎,併迴顧性分析1986年1月—2014年12月嗜痠細胞性膀胱炎患者179例文獻報道。結果嗜痠細胞性膀胱炎患者均經膀胱鏡檢查、活檢後經病理明確診斷。男119例,女61例,年齡0 fl.8~78(38.5±18.5)歲,常見癥狀有肉眼或鏡下血尿(68.89%)以及尿頻、尿急和尿痛(46.67%),其他癥狀還包括恥骨上疼痛(30.56%)、排尿睏難(30.00%)、腰痛(7.18%)、尿潴留(2.78%)等。絕大多數患者無異常體徵(86.11%),部分患者可有恥骨上壓痛(10.56%),下腹部包塊(3.33%)和腎區叩擊痛(3.33%)。影像學檢查異常暘性率依次是CT掃描93.50%(115/123)、膀胱B型超聲91.39%(138/151)和靜脈腎盂造影(IUV)77.65%(66/85)。膀胱鏡檢查病變呈多處和廣汎瀰漫性病變76例(44.71%),纍及膀胱三角區23例(13.53%),左、右或雙側輸尿管開口24例(14.12%),右側壁22例(12.94%),後壁19例(11.18%),膀胱底部13例(7.65%),左側壁和膀胱頂部各9例(5.29%),前壁和膀胱頸均為6例(3.53%)。併髮腎積水37例(20.55%),膀胱容量明顯縮小、膀胱充盈睏難或無法充盈19例(10.55%),尿潴留10例(5.56%),膀胱結石2例(1.11%),腫物錶麵沙粒樣鈣化和膀胱頸硬化癥各1例(0.56%)。確診後單純內科治療59例(32.78%),膀胱部分切除31例(17.22%),膀胱部分切除+內科治療25例(13.89%),膀胱鏡治療+內科治療23例(12.78%),單純膀胱鏡治療18例(10.00%),膀胱全切和膀胱自體擴大術各1例(0.56%),餘22例(12.22%)未詳述內科治療。本組病例中治愈156例(86.67%)。結論嗜痠細胞性膀胱炎可髮于各年齡段,男性多于女性。常見癥狀包括血尿,尿頻、尿急、尿痛,和恥骨上疼痛,排尿睏難等。經尿道切除膀胱病變,結閤皮質激素、抗過敏等綜閤治療,多數患者預後良好。
목적:분석국인기산세포성방광염림상특점,탐색림상진단급치료원칙。방법보고1례기산세포성방광염,병회고성분석1986년1월—2014년12월기산세포성방광염환자179예문헌보도。결과기산세포성방광염환자균경방광경검사、활검후경병리명학진단。남119례,녀61례,년령0 fl.8~78(38.5±18.5)세,상견증상유육안혹경하혈뇨(68.89%)이급뇨빈、뇨급화뇨통(46.67%),기타증상환포괄치골상동통(30.56%)、배뇨곤난(30.00%)、요통(7.18%)、뇨저류(2.78%)등。절대다수환자무이상체정(86.11%),부분환자가유치골상압통(10.56%),하복부포괴(3.33%)화신구고격통(3.33%)。영상학검사이상양성솔의차시CT소묘93.50%(115/123)、방광B형초성91.39%(138/151)화정맥신우조영(IUV)77.65%(66/85)。방광경검사병변정다처화엄범미만성병변76례(44.71%),루급방광삼각구23례(13.53%),좌、우혹쌍측수뇨관개구24례(14.12%),우측벽22례(12.94%),후벽19례(11.18%),방광저부13례(7.65%),좌측벽화방광정부각9례(5.29%),전벽화방광경균위6례(3.53%)。병발신적수37례(20.55%),방광용량명현축소、방광충영곤난혹무법충영19례(10.55%),뇨저류10례(5.56%),방광결석2례(1.11%),종물표면사립양개화화방광경경화증각1례(0.56%)。학진후단순내과치료59례(32.78%),방광부분절제31례(17.22%),방광부분절제+내과치료25례(13.89%),방광경치료+내과치료23례(12.78%),단순방광경치료18례(10.00%),방광전절화방광자체확대술각1례(0.56%),여22례(12.22%)미상술내과치료。본조병례중치유156례(86.67%)。결론기산세포성방광염가발우각년령단,남성다우녀성。상견증상포괄혈뇨,뇨빈、뇨급、뇨통,화치골상동통,배뇨곤난등。경뇨도절제방광병변,결합피질격소、항과민등종합치료,다수환자예후량호。
Objective To analyze the clinical characteristics of eosinophilic cystitis , explore the clinical diagnosis and treatment principles .Methods We reported 1 case of eosinophilic cystitis , and retrospective analysis the literature from January 1986 to December 2014 which related to eosinophilic cystitis .Results The eosinophilic cystitis patients were con-firmed by cystoscopy, biopsy.119 patients were male, 61 patients were female, the age were 0.8~78 (38.5 ±18.5) years, symptom included gross or microscopic hematuria (68.89%) and frequent urination, urgency, dysuria (46.67%).Other symptoms included suprapubic pain (30.56%), dysuria (30.00%), low back pain (7.18%), and urinary retention (2.78%).The vast majority of patients with no abnormal signs (86.11%), some patients showed suprapubic tenderness (10.56%), abdomen bag block (3.33%) and kidney area pain (3.33%).The abnormal positive rate of imaging examina-tion was 93.50%(115/123) of CT, 91.39%(138/151) of ultrasound, and 77.65%(66/85) of IVU.The lesions showed multiple and diffuse lesions in 76 cases (44.71%), bladder triangle area lesions in 23 cases (13.53%), left, right, and bi-lateral orificium ureteris in 24 cases (14.12%), right wall in 22 cases (12.94%), posterior wall in 19 cases (11.18%), bladder basal area in 13 cases (7.56%), left wall and bladder top area in 9 cases (5.29%), anterior wall and bladder neck in 6 cases (3.53%), and concurrent hydronephrosis in 37 cases (20.55%), significantly reduced bladder capacity ,bladder filling difficult or impossible to filling in 19 cases (10 M.55%), urinary retention in 10 patients (5.56%), bladder stones in 2 cases (1.11%), tumor surface sand-like calcification and bladder neck sclerosis in 1 case (0.56%).After the diagnosis, internal-medical therapy alone in 59 cases (32.78%), partial resection of the bladder in 31 cases (17.22%), partial cystec-tomy +medical treatment in 25 cases (13.89%), cystoscopy treatment +medical treatment in 23 cases (12.78%), sim-ple bladder mirror in 18 cases (10.00%), cystectomy and autologous bladder augmentation in 1 case (0.56%), and 22 ca-ses (12.22%) with medical treatment were not described in detail .The patients were cured of 156 cases (86.67%).Con-clusion The eosinophilic cystitis occurs in all ages , more men than women .Common symptoms including hematuria , urinary frequency, urgency, dysuria, and suprapubic pain, dysuria.Transurethral resection of bladder lesions , combined with corti-costeroid, anti-allergy and other comprehensive treatment , the majority of patients showed good prognosis .