CAJ | 학술논문

目的：探讨施行综合管理模式对癌症患者静脉化学治疗(简称化疗)用药安全的作用，为临床医务人员提供可靠的参考依据和解决方法。方法选取施行综合管理模式前的86例患者作为对照组，施行该模式后的86例患者作为观察组。对比分析两组用药不合理、药物丢弃、药物预处理不适当及不良事件发生情况。结果观察组用药不合理率为9.81%，明显低于对照组的23.22%（χ2=8.62，P﹤0.05）；观察组药物丢弃数量减少至0支，明显少于对照组的4支（χ2=5.02，P﹤0.05）；观察组药物预处理不适当占比11.92%，明显低于对照组的33.93%（χ2=6.39，P﹤0.05）；观察组不良事件发生率为2.32%，明显低于对照组的8.14%（χ2=4.66，P﹤0.05）。结论综合管理模式可保证癌症患者的用药安全，为临床医务人员提供参考依据和解决方法。
목적：탐토시행종합관리모식대암증환자정맥화학치료(간칭화료)용약안전적작용，위림상의무인원제공가고적삼고의거화해결방법。방법선취시행종합관리모식전적86례환자작위대조조，시행해모식후적86례환자작위관찰조。대비분석량조용약불합리、약물주기、약물예처리불괄당급불량사건발생정황。결과관찰조용약불합리솔위9.81%，명현저우대조조적23.22%（χ2=8.62，P﹤0.05）；관찰조약물주기수량감소지0지，명현소우대조조적4지（χ2=5.02，P﹤0.05）；관찰조약물예처리불괄당점비11.92%，명현저우대조조적33.93%（χ2=6.39，P﹤0.05）；관찰조불량사건발생솔위2.32%，명현저우대조조적8.14%（χ2=4.66，P﹤0.05）。결론종합관리모식가보증암증환자적용약안전，위림상의무인원제공삼고의거화해결방법。
Objective To investigate the effect of comprehensive management mode for ensuring drug safety of intravenous chemotherapy on cancer patients,and to provide a reliable and effective reference and solutions for clinical medical staff. Methods Before and after taking comprehensive management mode,86 patients were selected as the control group and the observation group respectively. The irra-tional drug use,drug discarding,the inappropriate medication and the incidence of adverse events were compared and analyzed in the two groups. Results The rate of irrational drug use in the observation group was 9. 81%,which was significantly lower than 23. 22%in the control group(χ2=8. 62,P ﹤ 0. 05);the number of discarded drugs was reduced to zero,which was significantly lower than 4 in the control group(χ2=5. 02,P ﹤ 0. 05);the rate of adverse events was 11. 92%,which was significantly lower than 33. 93% in the control group(χ2=6. 39,P ﹤ 0. 05);the occurrence rate of adverse events was 2. 32%,which was significantly lower than 8. 14% in the control group(χ2=4. 66,P ﹤ 0. 05). Conclusion Comprehensive management mode can ensure the drug safety of patients with cancer,and can provide the reference and solutions for clinical doctors.