CAJ | 학술논문

目的：总结移植肾毛霉菌感染的诊治经验。方法回顾性分析来自同一供体的两例移植肾毛霉菌感染致移植肾及动脉破裂病例的临床资料，并复习国内外相关文献。结果与结论肾移植术后毛霉菌感染无特异性表现，缺乏早期诊断手段，容易误诊、漏诊，其易致血管破裂，预后凶险。及早确诊，彻底清创，及时选择有效抗真菌药物及撤除免疫抑制剂，血栓弹力图监控下纠正机体凝血功能紊乱，可提高此类患者存活率。
목적：총결이식신모매균감염적진치경험。방법회고성분석래자동일공체적량례이식신모매균감염치이식신급동맥파렬병례적림상자료，병복습국내외상관문헌。결과여결론신이식술후모매균감염무특이성표현，결핍조기진단수단，용역오진、루진，기역치혈관파렬，예후흉험。급조학진，철저청창，급시선택유효항진균약물급철제면역억제제，혈전탄력도감공하규정궤체응혈공능문란，가제고차류환자존활솔。
Objective To summarize the diagnosis and treatment experience of mucor infection in renal grafts.Methods Clinical data of two patients with mucor infection in renal grafts from the same kidney donor that finally caused renal graft and renal artery rupture were retrospectively studied,and the relevant domestic and foreign literatures were reviewed. Results and conclusions Mucor infection after renal transplantation has no specific manifestation,thus it lacks of means of early diagnosis and is easy to cause misdiagnosis and missed diagnosis.Mucor infection is easy to cause vascular rupture and the prognosis is poor.Early diagnosis, thorough debridement, timely selection of effective antifungal agent, withdrawal of immunosuppressant and correction of coagulation disorders under the monitor of thrombelastogram may improve the survival rate of such patients.