CAJ | 학술논문

回顾性分析582 例辅助生殖技术助孕与自然受孕双胎妊娠中妊娠期肝内胆汁淤积症( ICP)的发生情况及其对围产期并发症的影响. 结果显示辅助生殖技术助孕双胎妊娠并发 ICP 为 8. 53%,自然受孕双胎妊娠并发 ICP 为16. 98%,发生重度ICP的比例分别为22. 73%、54. 55%. 辅助生殖技术助孕与自然受孕双胎妊娠并发ICP在围产期血清总胆汁酸、丙氨酸转移酶、门冬氨酸转移酶、入院孕周、分娩孕周、剖宫产率、Apgar评分、早产、胎膜早破、胎儿窘迫、产后24 h出血量方面比较,差异均无统计学意义. 辅助生殖技术组双胎妊娠并发ICP的新生儿出生体重大于自然受孕组. 辅助生殖技术助孕双胎妊娠并不增加ICP的发生率,围产期并发症无增加.
회고성분석582 례보조생식기술조잉여자연수잉쌍태임신중임신기간내담즙어적증( ICP)적발생정황급기대위산기병발증적영향. 결과현시보조생식기술조잉쌍태임신병발 ICP 위 8. 53%,자연수잉쌍태임신병발 ICP 위16. 98%,발생중도ICP적비례분별위22. 73%、54. 55%. 보조생식기술조잉여자연수잉쌍태임신병발ICP재위산기혈청총담즙산、병안산전이매、문동안산전이매、입원잉주、분면잉주、부궁산솔、Apgar평분、조산、태막조파、태인군박、산후24 h출혈량방면비교,차이균무통계학의의. 보조생식기술조쌍태임신병발ICP적신생인출생체중대우자연수잉조. 보조생식기술조잉쌍태임신병불증가ICP적발생솔,위산기병발증무증가.
To analyse intrahepatic cholestasia of pregnancy ( ICP) occurrence in 582 cases of twin pregnancy con-ceived by assisted reproductive techniques and natural conception retrospectively, and to analyse its influence on perinatal complications. The percentage in the group of assisted reproductive techniques twin pregnancies with ICP ( ART group) was 8. 53%, which was 16. 98% in the group of naturally conceived twin pregnancies with ICP( nat-urally conceived group) , and the severity of ICP in ART group was 22. 73%, which was 54. 55% in the naturally conceived group. To compare the two groups in TBA, ALT, AST, hospitalized pregnant weeks, the weeks of deliv-ery, the rate of cesarean section, the Apgar score, premature birth, premature rupture of membranes and fetal dis-tress, 24-hour postpartum hemorrhage volume, there were no statistically significant differences. The neonatal weight of ART group was greater than the naturally conceived group. Twin pregnancies conceived by assisted repro-ductive technology did not increase the incidence of ICP. And there were no differences in complications of perina-tal period.