中国实用医刊
中國實用醫刊
중국실용의간
Chinese Journal of Practical Medicine
2015年
20期
16-17
,共2页
支气管扩张症%急性感染%病原学%耐药性
支氣管擴張癥%急性感染%病原學%耐藥性
지기관확장증%급성감염%병원학%내약성
Bronchiectasis%Acute infection%Etiology%Resistance
目的：研究支气管扩张症患者急性加重期的病原学和耐药性分析。方法选取三门峡市中心医院收治的支气管扩张症急性感染患者287例,患者入院后取痰标本行病原菌分析,并行药敏感实验,了解细菌抗药性。结果本组287例患者中,186例痰液检查结果呈阳性,占64．81%。共分离出210株菌株,184株为革兰氏阴性球菌,占87．62%；其中铜绿假单细胞、肺炎克雷伯菌、大肠埃希菌、土生克雷伯菌所占几率相对较高,分别为30．48%、21．43%、13．33%、7．14%。分析病原菌耐药性,铜绿假单细胞、肺炎克雷伯菌、大肠埃希菌、土生克雷伯菌对氨苄西林的耐药性最高,分别为90．63%、95．56%、89．29%、100%,其次为头孢呋辛,分别为100%、75．56%、89．29%、100%,对妥布霉素、阿米卡星的耐药率相对较低,分别为7．81%、17．19%,11．11%、15．56%,10．71%、0,0、0。结论支气管扩张症感染患者以革兰氏阴性球菌感染为主,病原菌对氨苄西林、头孢呋辛等药物的耐药性相对较高,用药前可先行药敏实验,提高用药合理性。
目的：研究支氣管擴張癥患者急性加重期的病原學和耐藥性分析。方法選取三門峽市中心醫院收治的支氣管擴張癥急性感染患者287例,患者入院後取痰標本行病原菌分析,併行藥敏感實驗,瞭解細菌抗藥性。結果本組287例患者中,186例痰液檢查結果呈暘性,佔64．81%。共分離齣210株菌株,184株為革蘭氏陰性毬菌,佔87．62%；其中銅綠假單細胞、肺炎剋雷伯菌、大腸埃希菌、土生剋雷伯菌所佔幾率相對較高,分彆為30．48%、21．43%、13．33%、7．14%。分析病原菌耐藥性,銅綠假單細胞、肺炎剋雷伯菌、大腸埃希菌、土生剋雷伯菌對氨芐西林的耐藥性最高,分彆為90．63%、95．56%、89．29%、100%,其次為頭孢呋辛,分彆為100%、75．56%、89．29%、100%,對妥佈黴素、阿米卡星的耐藥率相對較低,分彆為7．81%、17．19%,11．11%、15．56%,10．71%、0,0、0。結論支氣管擴張癥感染患者以革蘭氏陰性毬菌感染為主,病原菌對氨芐西林、頭孢呋辛等藥物的耐藥性相對較高,用藥前可先行藥敏實驗,提高用藥閤理性。
목적：연구지기관확장증환자급성가중기적병원학화내약성분석。방법선취삼문협시중심의원수치적지기관확장증급성감염환자287례,환자입원후취담표본행병원균분석,병행약민감실험,료해세균항약성。결과본조287례환자중,186례담액검사결과정양성,점64．81%。공분리출210주균주,184주위혁란씨음성구균,점87．62%；기중동록가단세포、폐염극뢰백균、대장애희균、토생극뢰백균소점궤솔상대교고,분별위30．48%、21．43%、13．33%、7．14%。분석병원균내약성,동록가단세포、폐염극뢰백균、대장애희균、토생극뢰백균대안변서림적내약성최고,분별위90．63%、95．56%、89．29%、100%,기차위두포부신,분별위100%、75．56%、89．29%、100%,대타포매소、아미잡성적내약솔상대교저,분별위7．81%、17．19%,11．11%、15．56%,10．71%、0,0、0。결론지기관확장증감염환자이혁란씨음성구균감염위주,병원균대안변서림、두포부신등약물적내약성상대교고,용약전가선행약민실험,제고용약합이성。
Objective To analyze the etiology and drug resistance of bronchiectasis patients with infection on acute exacerbation. Methods Two hundred and eighty-seven bronchiectasis patients with a-cute infection were taken pathogen analysis and medicine sensitive experiment, and the drug resistance in bacteria was observed. Results Sputum examination results of 186 cases(64. 81%) were positive. Two hundred and ten bacterial strains were separated and 184 strains (87. 62%) were gram-negative coccus. The pseudomonas aeruginosa, klebsiella pneumoniae, E. coli, klebsiella terrigena accounted for 30. 48%, 21. 43%, 13. 33% and 7. 14% respectively. Pseudomonas aeruginosa, klebsiella pneumoniae, E. coli, klebsiella terrigena had the highest resistance to ampicillin (90. 63%,95. 56%,89. 29%,100% respective-ly), followed by cefuroxime (100. 0%,75. 56%,89. 29%,100% respectively). They had relatively low re-sistance to tobromycin and amikacin. Conclusions Bronchiectasis infection are mainly gram-negative bac-teria infection. Pathogenic bacteria has high resistance to drugs like ampicillin and cefuroixime. Taking the medicine sensitive experiment before medication, in order to improve the rationality of medication.
