CAJ | 학술논문

目的：探讨肺结核合并2型糖尿病患者T淋巴细胞亚群的变化及其与血糖控制水平相关性。方法利用流式细胞术检测外周血淋巴细胞亚群水平，用免疫比浊法检测糖化血红蛋白水平。结果 HbAlc <7％，DM+LTB与DM两组的CD3+，CD4+、CD8+、CD4+/CD8+无统计学差异（P>0.05）；HbAlc >7％，DM+LTB与DM两组的CD3+，CD4+、CD8+、CD4+/CD8+有统计学差异（P<0.05）。结论长期高血糖状态会加重肺结核合并2型糖尿病患者细胞免疫功能紊乱。
목적：탐토폐결핵합병2형당뇨병환자T림파세포아군적변화급기여혈당공제수평상관성。방법이용류식세포술검측외주혈림파세포아군수평，용면역비탁법검측당화혈홍단백수평。결과 HbAlc <7％，DM+LTB여DM량조적CD3+，CD4+、CD8+、CD4+/CD8+무통계학차이（P>0.05）；HbAlc >7％，DM+LTB여DM량조적CD3+，CD4+、CD8+、CD4+/CD8+유통계학차이（P<0.05）。결론장기고혈당상태회가중폐결핵합병2형당뇨병환자세포면역공능문란。
Objective To discuss the correlation of T lymphocyte subsets and blood glucose level in patients with pulmonary tuberculosis complicated with type 2 diabetes melitus. Methods Flow cytometry was used to detect the levels of peripheral blood lymphocyte subsets, and the level of glycosylated hemoglobin was detected by using the immune assay.ResultsThere had no statistical significance in CD3+, CD4+, CD8+, CD4+/CD8+ between DM+LTB and DM group(P> 0.05)( HbAlc < 7%). While HbAlc > 7%, there had statistical significance(P< 0.05).Conclusion Long-term high blood glucose status can increase the celular immune function in patients with pulmonary tuberculosis complicated with type 2 diabetes melitus.