CAJ | 학술논문

【目的】探讨不同营养支持治疗对胃肠道肿瘤术后患者疗效的影响。【方法】选取2013年5月至2014年6月在本院肿瘤科诊治的87例胃肠道肿瘤患者,随机分为对照组43例,观察组44例,对照组在常规治疗的基础上采用肠外营养,观察组在对照组的基础上加用肠内营养治疗,连续治疗2周后比较两组患者的生化指标、排气时间、排便时间、肿瘤坏死因子-α(TNF-α)、白细胞介素-2(IL-2)、IL-6、IL-10水平及术后并发症情况。【结果】观察组患者的排气时间、排便时间与对照组比较明显缩短(P <0.05)；IL-2、IL-6、IL-10水平较术前升高(P <0.05),TNF-α较术前降低(P <0.05)；观察组并发症的发生率也较对照组低(P <0.05)。【结论】肠内肠外营养支持治疗对胃肠道肿瘤术后患者具有较好的治疗作用,能缩短胃肠功能恢复的时间,降低炎症反应和并发症的发生率。
【목적】탐토불동영양지지치료대위장도종류술후환자료효적영향。【방법】선취2013년5월지2014년6월재본원종류과진치적87례위장도종류환자,수궤분위대조조43례,관찰조44례,대조조재상규치료적기출상채용장외영양,관찰조재대조조적기출상가용장내영양치료,련속치료2주후비교량조환자적생화지표、배기시간、배편시간、종류배사인자-α(TNF-α)、백세포개소-2(IL-2)、IL-6、IL-10수평급술후병발증정황。【결과】관찰조환자적배기시간、배편시간여대조조비교명현축단(P <0.05)；IL-2、IL-6、IL-10수평교술전승고(P <0.05),TNF-α교술전강저(P <0.05)；관찰조병발증적발생솔야교대조조저(P <0.05)。【결론】장내장외영양지지치료대위장도종류술후환자구유교호적치료작용,능축단위장공능회복적시간,강저염증반응화병발증적발생솔。
[Objective]To explore the impact of different nutritional support methods on the efficacy of pa-tients with gastroenteric carcinoma after operation.[Methods]Totally 87 patients with gastroenteric carcino-ma in oncology department of our hospital from May 2013 to Jun.2014 were chosen and randomly divided into control group(n =43)and observation group(n =44).The control group received parenteral nutrition based on routine treatment,while the observation group received enteral nutrition based on the treatment of control group.After continuous treatment for 2 weeks,the biochemical index,exhaust time,defecation time,the lev-els of tumor necrosis factor-alpha(TNF-ɑ),interleukin-1 (IL-2),interleukin-6 (IL-6 ),interleukin-10 (IL-10) and postoperative complications between two groups were compared.[Results]The exhaust time and defeca-tion time in observation group were shorter than those in control group(P <0.01).Compared to the pre-oper-ation,the levels of IL-2,IL-6 and IL-10 were increased(P <0.05),while the level of TNF-ɑwas decreased( P <0.05).The incidence of complications in observation group was lower than that in control group(P <0.05).[Conclusion]Both enteral nutrition support and parenteral nutrition support have good therapeutic effect for patients with gastroenteric carcinoma after operation,and can shorten the recovery time of gastroin-testinal function and reduce inflammation and the incidence of complications.