CAJ | 학술논문

目的观察50%硫酸镁联合维生素B12与50%葡萄糖混合液外敷治疗盐酸阿霉素引起的化疗性静脉炎的效果.方法将24只家兔随机分为4组,经耳缘静脉输入浓度为0.2%的盐酸阿霉素试剂10 ml,注射速度为99 ml/h,双耳同时注射.给药后48 h采取不同的干预措施:50%硫酸镁湿敷(A组);维生素B12+50%葡萄糖混合液湿敷(B组);50%硫酸镁+维生素B12+50%葡萄糖湿敷(C组);空白对照组(D组)无干预;2次/d,干预1周后进行结果分析.结果 50%硫酸镁联合维生素B12与50%葡萄糖混合液外敷治疗静脉炎的效果显著提高(P<0.05).结论 50%硫酸镁联合维生素B12与50%葡萄糖混合液外敷可以显著提高化疗性静脉炎的治愈率.
목적 관찰50%류산미연합유생소B12여50%포도당혼합액외부치료염산아매소인기적화료성정맥염적효과.방법장24지가토수궤분위4조,경이연정맥수입농도위0.2%적염산아매소시제10 ml,주사속도위99 ml/h,쌍이동시주사.급약후48 h채취불동적간예조시:50%류산미습부(A조);유생소B12+50%포도당혼합액습부(B조);50%류산미+유생소B12+50%포도당습부(C조);공백대조조(D조)무간예;2차/d,간예1주후진행결과분석.결과 50%류산미연합유생소B12여50%포도당혼합액외부치료정맥염적효과현저제고(P<0.05).결론 50%류산미연합유생소B12여50%포도당혼합액외부가이현저제고화료성정맥염적치유솔.
Objective To observe the effect of mixture topical of 50% MgSO4 combined with vitamin B12 and 50% glucose in the treatment of phlebitis induced by doxorubicin hydrochloride.Methods Twenty four rabbits were randomly divided into four groups. All rabbits received the injection of 0.2% doxorubicin hydrochloride accounting for 10 ml with an injection velocity of 99 ml/h through the veins in two ear of each rabbit. Forty eight hours after the injection, four different treatments were performed. Rabbits in group A were treated with 50% MgSO4, rabbits in group B were treated with vitamin B12 and 50% glucose, rabbits in group C were treated with 50% MgSO4, vitamin B12 and 50% glucose. The control group (group D) had no treatment. The treatment were performed twice per day and lasted for 1 week, then the results were analyzed.Results Compared with other groups, the efficiency of the treatment in group C was the highest of all (P<0.05).ConclusionThe treatment of mixture topical of 50% MgSO4 combined with vitamin B12 and 50% glucose can significantly improve the cure rate of chemotherapeutic phlebitis.