中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2015年
34期
2799-2801
,共3页
呼吸道感染%肺炎,病毒性%xTAG呼吸道病毒多重检测技术
呼吸道感染%肺炎,病毒性%xTAG呼吸道病毒多重檢測技術
호흡도감염%폐염,병독성%xTAG호흡도병독다중검측기술
Respiratory tract infections%Pneumonia,viral%xTAG Respiratory Virus Panel Array
目的 分析疑似病毒性肺炎住院患者xTAG呼吸道病毒多重检测技术(xTAG RVP)的检测结果.方法 将2013年1月至2014年12月北京协和医院133例疑似病毒性肺炎住院患者分为中青年组(17 ～ 49岁)42例和中老年组(50～88岁)91例,采集患者的深部痰或支气管肺泡灌洗液,利用xTAG RVP试剂盒对标本进行核酸检测,并对结果进行分析.结果 133例标本中,有50例可以检测出病毒,阳性率为37.6％;阳性标本中混合感染占12.0％.其中甲型流感病毒和鼻病毒检出率最高(45.0％和16.7％).中青年组感染率显著高于中老年组(73.8％比31.9％,P＜0.001).春夏秋冬四季呼吸道病毒阳性检出率分别为25.0％、6.7％、20.0％、38.3％,差异无统计学意义(P=0.257).结论 疑似病毒性肺炎住院患者xTAG RVP检测的常见病原体为甲型流感病毒和鼻病毒,中青年患者感染率高于中老年患者.
目的 分析疑似病毒性肺炎住院患者xTAG呼吸道病毒多重檢測技術(xTAG RVP)的檢測結果.方法 將2013年1月至2014年12月北京協和醫院133例疑似病毒性肺炎住院患者分為中青年組(17 ～ 49歲)42例和中老年組(50～88歲)91例,採集患者的深部痰或支氣管肺泡灌洗液,利用xTAG RVP試劑盒對標本進行覈痠檢測,併對結果進行分析.結果 133例標本中,有50例可以檢測齣病毒,暘性率為37.6％;暘性標本中混閤感染佔12.0％.其中甲型流感病毒和鼻病毒檢齣率最高(45.0％和16.7％).中青年組感染率顯著高于中老年組(73.8％比31.9％,P＜0.001).春夏鞦鼕四季呼吸道病毒暘性檢齣率分彆為25.0％、6.7％、20.0％、38.3％,差異無統計學意義(P=0.257).結論 疑似病毒性肺炎住院患者xTAG RVP檢測的常見病原體為甲型流感病毒和鼻病毒,中青年患者感染率高于中老年患者.
목적 분석의사병독성폐염주원환자xTAG호흡도병독다중검측기술(xTAG RVP)적검측결과.방법 장2013년1월지2014년12월북경협화의원133례의사병독성폐염주원환자분위중청년조(17 ～ 49세)42례화중노년조(50～88세)91례,채집환자적심부담혹지기관폐포관세액,이용xTAG RVP시제합대표본진행핵산검측,병대결과진행분석.결과 133례표본중,유50례가이검측출병독,양성솔위37.6％;양성표본중혼합감염점12.0％.기중갑형류감병독화비병독검출솔최고(45.0％화16.7％).중청년조감염솔현저고우중노년조(73.8％비31.9％,P＜0.001).춘하추동사계호흡도병독양성검출솔분별위25.0％、6.7％、20.0％、38.3％,차이무통계학의의(P=0.257).결론 의사병독성폐염주원환자xTAG RVP검측적상견병원체위갑형류감병독화비병독,중청년환자감염솔고우중노년환자.
Objective To analyze the testing results of hospitalized patients with suspected viral pneumonia using xTAG Respiratory Virus Panel Array (xTAG RVP).Methods 133 hospitalized patients with suspected viral pneumonia from Peking Union Medical College Hospital from January 2013 to December 2014 were divided into two groups,including 42 young and middle-aged patients (17-49 years old) and 91 middle and old-aged patients (50-88 years old).The nucleic acids of sputum or bronchoalveolar lavage fluid (BALF) samples from the two group patients were screened by xTAG RVP and the results were analyzed.Results Viruses can be detected from 50 out of all 133 samples,and the positive rate was 37.6％.Among the viral positive samples,the proportion of mixed infections was 12.0％.The detection rates of Influenza A virus (FluA) and Rhinovirus (RV) were higher than others (45.0％ and 16.7％).The infection rate of young and middle-aged patients was significantly higher than that of the middle and oldaged patients (73.8％ vs 31.9％,P ＜0.001).The viral detection rates of samples from spring,summer,autumn and winter were 25.0％,6.7％,20.0％ and 38.3％,respectively.The positive rate difference among four seasons was not significant (P =0.257).Conclusion FluA and RV are dominant respiratory viruses in hospitalized patients with suspected viral pneumonia,and the infection rate of the young and middle-aged patients is higher than the middle and old-aged patients.
