CAJ | 학술논문

回顾性分析97例在白光内镜下疑诊为早期食管鳞癌或癌前病变的患者，进行窄带谱成像放大内镜（NBI-ME）检查，行靶向活检，最终经内镜下切除或者手术切除确定病灶性质。分析病变的 NBI-ME 的形态特点，并与活检病理、内镜切除或手术切除标本病理进行对照。在97例患者中最终确诊为鳞癌35例，高级别上皮内瘤变62例。NBI-ME 诊断为鳞癌或高级别上皮内瘤变的有95例，诊断准确性达97．9％。经过靶向活检，有10例原诊断为低级别上皮内瘤变或炎症的患者被诊断为鳞癌或高级别上皮内瘤变，准确性提高52．6％。而根据乳头内毛细血管袢的形态，对肿瘤浸润深度判断的准确性达到81．4％。
회고성분석97례재백광내경하의진위조기식관린암혹암전병변적환자，진행착대보성상방대내경（NBI-ME）검사，행파향활검，최종경내경하절제혹자수술절제학정병조성질。분석병변적 NBI-ME 적형태특점，병여활검병리、내경절제혹수술절제표본병리진행대조。재97례환자중최종학진위린암35례，고급별상피내류변62례。NBI-ME 진단위린암혹고급별상피내류변적유95례，진단준학성체97．9％。경과파향활검，유10례원진단위저급별상피내류변혹염증적환자피진단위린암혹고급별상피내류변，준학성제고52．6％。이근거유두내모세혈관번적형태，대종류침윤심도판단적준학성체도81．4％。
97 patients who were suspected of early stage of esophageal squamous cancer or precancerous lesions were enrolled.The lesions were rechecked using narrow band imaging magnifying endoscopy(NBI-ME),then target biopsy were conducted.All patients received endoscopic resection or surgery.The features of all the lesions under NBI-ME and the pathological results of biopsy,endoscopic resection or surgical specimen were compared.The pa-tients were diagnosed with 35 cases of squamous cancer and 62 cases of high grade intraepithelia neoplasia(HGIN) according to the pathological results of endoscopic resection or surgical specimen.We diagnosed 95 cases of cancer or HGIN according to the NBI-ME feature,the diagnostic accuracy was 97.9%.10 cases with former diagnosis of low grade intraepithelia neoplasia(LGIN)or inflammation were changed to cancer or HGIN according to target biop-sy.The progressive rate of target biopsy was 52.6%.While the diagnostic accuracy of invasive depth of the lesions was 81.4% according to the features of intraepithelial papillary capillary loop(IPCL).