应用化工
應用化工
응용화공
Applied Chemical Industry
2015年
9期
1617-1620,1626
,共5页
喹啉-2-羧酸%金属卟啉%仿生催化%2-甲基喹啉%反应机理
喹啉-2-羧痠%金屬卟啉%倣生催化%2-甲基喹啉%反應機理
규람-2-최산%금속계람%방생최화%2-갑기규람%반응궤리
quinoline-2-carboxylic acid%metalloporphyrins%biomimetic catalysis%2-methyl-quinoline%reaction mechanism
研究了在温和的条件下,金属卟啉催化氧气氧化2-甲基喹啉为喹啉-2-羧酸的新的绿色合成方法。重点考察了金属卟啉种类及用量、反应温度和压力、反应时间、碱的浓度、溶剂种类等不同影响因素对反应的影响。结果表明,在最优的反应条件下(120℃,1.5 MPa,8 h,4×10-5mol/L的T(p-OCH3)PPCoCl,1.6 mol/L的NaOH,溶剂为乙醇)2-甲基喹啉的转化率达到了40.75%,喹啉-2-羧酸的选择性和收率分别达到了24.59%和10.02%,并研究了该反应的机理。
研究瞭在溫和的條件下,金屬卟啉催化氧氣氧化2-甲基喹啉為喹啉-2-羧痠的新的綠色閤成方法。重點攷察瞭金屬卟啉種類及用量、反應溫度和壓力、反應時間、堿的濃度、溶劑種類等不同影響因素對反應的影響。結果錶明,在最優的反應條件下(120℃,1.5 MPa,8 h,4×10-5mol/L的T(p-OCH3)PPCoCl,1.6 mol/L的NaOH,溶劑為乙醇)2-甲基喹啉的轉化率達到瞭40.75%,喹啉-2-羧痠的選擇性和收率分彆達到瞭24.59%和10.02%,併研究瞭該反應的機理。
연구료재온화적조건하,금속계람최화양기양화2-갑기규람위규람-2-최산적신적록색합성방법。중점고찰료금속계람충류급용량、반응온도화압력、반응시간、감적농도、용제충류등불동영향인소대반응적영향。결과표명,재최우적반응조건하(120℃,1.5 MPa,8 h,4×10-5mol/L적T(p-OCH3)PPCoCl,1.6 mol/L적NaOH,용제위을순)2-갑기규람적전화솔체도료40.75%,규람-2-최산적선택성화수솔분별체도료24.59%화10.02%,병연구료해반응적궤리。
The novel green synthesis method of 2-methyl-quinoline to quinoline-2-carboxylic acid cata-lyzed by metalloporphyrins under mild conditions with molecular oxygen was reported. Different influen-cing factors including type and content of the catalyst,reaction temperature and pressure,reaction time, concentration of sodium hydroxide and solvent were investigated. The results showed under the optimal conditions:4. 0 × 10 -5 mol/L T(p-OCH3)PPCoCl,1. 6 mol/L NaOH and 1. 5 MPa of the oxygen pressure at 120 ℃ for 8 h ethanol as solvent,conversion rate of 2-methyl-quinoline reached 40. 75%,and the se-lectivity and the yield of quinoline-2-carboxylic acid reached 24. 59% and 10. 02%,respectively,and the reaction mechanism was studied.
