CAJ | 학술논문

目的探讨不同电极裸露端长度、不同消融时间对转换器介导的多电极同步消融离体牛肝消融灶大小的影响.方法 2014年12月至2015年2月在中山大学实验动物中心采用Cool-tip转换控制器介导的多电极同步射频消融设备,以不同电极裸露端长度(2、3、4 cm)和不同消融时间(12、16、20、24 min)为变量形成12种组合消融新鲜离体牛肝,测量消融灶纵径、横径并计算其体积,采用单因素方差分析法、t检验分析消融灶大小的影响因素.结果裸露端3 cm电极形成消融灶类圆率更接近1.当采用裸露端4 cm、电极消融24 min时消融灶达到最大,纵径为(7.66±0.21) cm、横径为(6.50 ±0.34) cm、体积为(172±12) cm3.在消融时间一定时,消融灶纵径、横径、体积随着电极裸露端的长度增加而增大,除裸露端3、4 cm电极的横径差异无统计学意义外,各组指标差异均有统计学意义(均P＜0.01).在电极裸露端长度一定时,消融灶纵径、横径、体积总体上随着消融时间的增加而增大,但除了裸露端4 cm电极在消融时间20、24 min的消融灶纵径和体积差异均有统计学意义(均P＜0.05)外,其余各组在相邻时间点的消融灶纵径、横径和体积差异均无统计学意义.结论在电极裸露端2～4 cm、消融时间12 ～ 24 min范围内,Cool-tip转换控制器介导的多电极同步射频消融灶的大小随电极裸露端长度和消融时间的增加而增大,其中裸露端3 cm电极形成消融灶更近似圆球体.
목적 탐토불동전겁라로단장도、불동소융시간대전환기개도적다전겁동보소융리체우간소융조대소적영향.방법 2014년12월지2015년2월재중산대학실험동물중심채용Cool-tip전환공제기개도적다전겁동보사빈소융설비,이불동전겁라로단장도(2、3、4 cm)화불동소융시간(12、16、20、24 min)위변량형성12충조합소융신선리체우간,측량소융조종경、횡경병계산기체적,채용단인소방차분석법、t검험분석소융조대소적영향인소.결과 라로단3 cm전겁형성소융조류원솔경접근1.당채용라로단4 cm、전겁소융24 min시소융조체도최대,종경위(7.66±0.21) cm、횡경위(6.50 ±0.34) cm、체적위(172±12) cm3.재소융시간일정시,소융조종경、횡경、체적수착전겁라로단적장도증가이증대,제라로단3、4 cm전겁적횡경차이무통계학의의외,각조지표차이균유통계학의의(균P＜0.01).재전겁라로단장도일정시,소융조종경、횡경、체적총체상수착소융시간적증가이증대,단제료라로단4 cm전겁재소융시간20、24 min적소융조종경화체적차이균유통계학의의(균P＜0.05)외,기여각조재상린시간점적소융조종경、횡경화체적차이균무통계학의의.결론 재전겁라로단2～4 cm、소융시간12 ～ 24 min범위내,Cool-tip전환공제기개도적다전겁동보사빈소융조적대소수전겁라로단장도화소융시간적증가이증대,기중라로단3 cm전겁형성소융조경근사원구체.
Objective To investigate the effects of different electrode exposed end and different ablated time on lesion size of Cool-tip multi-electrode synchronous radiofrequency ablation via switching controller in ex vivo bovine liver.Method Twelve combinations of different electrode exposed end (2 cm,3 cm and 4 cm) were used,and different ablated time (12,16,20 and 24 mins) was as experimental parameter.Ablated lesions in longitudinal diameter,transverse diameter and volume were measured.Analyze the factors influencing the lesion size with ANOVA or t test.Results The ablated lesions with 3 cm exposed end electrodes were more stable and the spheroidal rate is more close to 1.When ablated 24 mins with 4 cm exposed end electrodes,the longitudinal diameter,transverse diameter and volume were (7.66 ± 0.21),(6.50±0.34) cm and (172 ± 12) cm3,respectively.When the ablated time was constant,the lesions increased with the exposed end length of the electrodes increased.All the data among groups was statistically significant (P ＜ 0.01) unless the transverse diameters between 3 and 4 cm exposed end electrode.When the exposed end length of electrodes was constant,the lesions increased with the ablated time increased as a whole.But there was no significant difference in most of the adjacent groups.Only the longitudinal diameters and volumes of 4 cm exposed end electrodes between 20 and 24 min were statistically significant(P ＜ 0.05) Conclusion Within the experimental range,the lesion size ablated by Cool-tip multi-electrode synchronous radiofrequency ablation via switching controller increased with the electrode exposed end and ablated time increased.The spheroidal rate of the ablated lesions with 3 em exposed end is more close to 1.