CAJ | 학술논문

【目的】观察不同年龄段小儿肺炎合并肺实变的临床特点。【方法】回顾性分析本院2012年8月至2014年8月期间收治的128例肺炎合并肺实变患儿的临床资料。【结果】<1岁和1~3岁的患儿白细胞(WBC)异常者所占比例最多,分别为49.0%(23/47)和57.6%(19/33),不同年龄患儿 WBC 比较,差异具有统计学意义(P <0.05)；<1岁组患儿住院时间分别大于3~5岁和≥5岁组患儿,差异均有统计学意义(P <0.05)；1~3岁组患儿机械通气和并发闭塞性细支气管炎(bronchitis obliterans,BO)所占比例最高,不同年龄患儿机械通气和并发 BO 情况比较,差异均有统计学意义(P <0.05)；肺炎链球菌占7.0%(9/128),排在细菌感染的首位,腺病毒占12.5%(16/128)排在病毒感染的首位,支原体感染占39.8%(51/128)；并发 BO 的患儿使用机械通气和纤支镜灌洗的比例明显高于未并发 BO 的患儿,两者之间的差异均有统计学意义(P <0.05)；并发 BO 的患儿住院时间和入院后发热时间高于未并发 BO 的患儿,两者之间的差异均有统计学意义(P <0.05)。【结论】婴幼儿是患肺炎合并肺实变的重点人群,肺炎链球菌、腺病毒和支原体是小儿肺炎合并肺实变病例的常见的病原体；肺炎合并肺实变并应用机械通气的患儿,应提前给予干预和综合治疗,以避免BO 的发生。
【목적】관찰불동년령단소인폐염합병폐실변적림상특점。【방법】회고성분석본원2012년8월지2014년8월기간수치적128례폐염합병폐실변환인적림상자료。【결과】<1세화1~3세적환인백세포(WBC)이상자소점비례최다,분별위49.0%(23/47)화57.6%(19/33),불동년령환인 WBC 비교,차이구유통계학의의(P <0.05)；<1세조환인주원시간분별대우3~5세화≥5세조환인,차이균유통계학의의(P <0.05)；1~3세조환인궤계통기화병발폐새성세지기관염(bronchitis obliterans,BO)소점비례최고,불동년령환인궤계통기화병발 BO 정황비교,차이균유통계학의의(P <0.05)；폐염련구균점7.0%(9/128),배재세균감염적수위,선병독점12.5%(16/128)배재병독감염적수위,지원체감염점39.8%(51/128)；병발 BO 적환인사용궤계통기화섬지경관세적비례명현고우미병발 BO 적환인,량자지간적차이균유통계학의의(P <0.05)；병발 BO 적환인주원시간화입원후발열시간고우미병발 BO 적환인,량자지간적차이균유통계학의의(P <0.05)。【결론】영유인시환폐염합병폐실변적중점인군,폐염련구균、선병독화지원체시소인폐염합병폐실변병례적상견적병원체；폐염합병폐실변병응용궤계통기적환인,응제전급여간예화종합치료,이피면BO 적발생。
[Objective]To explore the clinical characters of pneumonia with pulmonary consolidation in children.[Methods]Case series analysis method was used,and 128 cases with pulmonary consolidation in pneu-monia from August,2012 to August,2014 were retrospectively investigated.[Results]The WBC level of <1 and 1~3 years old children with pneumonia and lung consolidation were respectively 49.0% and 57.6%.There was a significant difference between these two group (P <0.05).The hospitalization of <1 years old children with pneumonia and lung consolidation was significantly longer than 3~5 and ≥5 years old children.The need of mechanical ventilation and the occurrence of bronchitis obliterans in the children with pneumonia and lung consolidation were highest.Streptococcus pneumonia (9 case,7.0%),adenovirus (1 6 case,12.5%)and my-coplasma (5 1 case,39.8%)were the most common infections.The proportion of using mechanical ventilation and fiberoptic bronchoscopy of bronchitis obliterans in the children with pneumonia and lung consolidation were significantly higher than the others (P <0.05),so were the days of hospitalization and the duration of fever after admission.[Conclusion]Infants with pneumonia accompanied with lung consolidation should be paid more attention.Streptococcus pneumoniae,adenovirus and mycoplasma were the most common etiology.In addi-tion,children used mechanical ventilation with pneumonia accompanied with lung consolidation should be given early intervention and comprehensive treatment so as to prevent the occurrence of ronchitis obliterans.