CAJ | 학술논문

目的：分析试管婴儿的孕妇发生先兆流产的相关影响因素，为预防试管婴儿孕妇发生先兆流产提供科学依据。方法病例组选取因患先兆流产而住院的孕妇87例；对照组均来自于同期做试管婴儿且无先兆流产的孕妇，共92例，调查试管婴儿孕妇先兆流产的影响因素。应用 EpiData3．1数据库及 SPSS 17．0软件进行数据录入及统计分析，分析方法主要包括秩和检验、χ2检验、单因素和多因素条件 Logistic回归分析；并计算各影响因素与先兆流产的关联强度（OR值）及其95％CI。结果单因素分析结果表明：两组研究对象的职业、文化程度、身高、体重、体质指数差异无统计学意义（P ＞0．05）。但年龄差异有统计学意义（P ＜0．05），两组研究对象在不良妊娠史、既往疾病史、不孕类型、不孕年限方面差异无统计学意义（P ＞0．05）；而两组在移植时子宫内膜厚度、移植的胚胎数目、移植胚胎的周期类型、孕妇的焦虑评分显示有统计学意义。多因素条件 Logistic 回归分析结果显示，胚胎移植时子宫内膜的厚度、移植胚胎的周期类型、妊娠期心理压力是先兆流产发生的独立危险因素（OR ＝1．169、0．304、0．898，95％CI 分别为1．005～1．361、0．135～0．683、0854～0．944）。结论移植时子宫内膜厚度、移植胚胎的周期类型、妊娠期心理压力可能是先兆流产发生的独立危险因素。
목적：분석시관영인적잉부발생선조유산적상관영향인소，위예방시관영인잉부발생선조유산제공과학의거。방법병례조선취인환선조유산이주원적잉부87례；대조조균래자우동기주시관영인차무선조유산적잉부，공92례，조사시관영인잉부선조유산적영향인소。응용 EpiData3．1수거고급 SPSS 17．0연건진행수거록입급통계분석，분석방법주요포괄질화검험、χ2검험、단인소화다인소조건 Logistic회귀분석；병계산각영향인소여선조유산적관련강도（OR치）급기95％CI。결과단인소분석결과표명：량조연구대상적직업、문화정도、신고、체중、체질지수차이무통계학의의（P ＞0．05）。단년령차이유통계학의의（P ＜0．05），량조연구대상재불량임신사、기왕질병사、불잉류형、불잉년한방면차이무통계학의의（P ＞0．05）；이량조재이식시자궁내막후도、이식적배태수목、이식배태적주기류형、잉부적초필평분현시유통계학의의。다인소조건 Logistic 회귀분석결과현시，배태이식시자궁내막적후도、이식배태적주기류형、임신기심리압력시선조유산발생적독립위험인소（OR ＝1．169、0．304、0．898，95％CI 분별위1．005～1．361、0．135～0．683、0854～0．944）。결론이식시자궁내막후도、이식배태적주기류형、임신기심리압력가능시선조유산발생적독립위험인소。
Objective To analyze the related factors of test tube babies of pregnant women with threatened abor-tion,and provide scientific basis for prevention of test tube babies of pregnant women with threatened abortion. Methods Patients of the prevalence of threatened abortion pregnant women were admitted to hospital in the same period;control group were from IVF and threatened abortion of pregnant women.The case group 87 cases,control group 92 cases,were selected influence factors investigation in august test tube babies of women with threatened a-bortion.Double transmission ratio error correction logic input,EpiData3.1 and SPSS 17.0 software were used to in-put and statistical analysis,methods mainly included signed-rank test,chisquare test,regression analysis,univari-ate and multivariate Logistic were used;and calculating the strength of association and the influence factors of threatened abortion (OR value)and 95%CI.Results Univariate analysis results showed that:the two groups had no statistical significance in the study of occupation,education level,height,weight,body mass index (P >0.05) difference.The age difference (P <0.05),the object of study in adverse pregnancy history,history of disease, type of infertility,infertility duration was not significant;while the two group at the time of transplantation of endo-metrial thickness,number of embryo transplantation,transplantation of embryonic period,pregnant anxiety scores had statistical significance.Multivariate Logistic regression analysis showed that,at the time of transplantation em-bryo endometrial thickness,type,the cycle pregnancy psychological pressure was the independent risk factors of threatened abortion(OR =1.169,0.304,0.898;95%CI were 1.005 ~1.361,0.135 ~0.683,0854 ~0.944). Conclusion Transplantation of endometrial thickness,embryo transfer cycle,pregnancy psychological stress may be the independent risk factors of threatened abortion.