CAJ | 학술논문

目的：评价科玛嘉念珠菌培养基鉴别常见致病性念珠菌的准确性。方法检索MEDLINE、EMBase、中国生物医学文献数据库（CBM ）、中文科技期刊全文数据库（CSJD）、中国期刊全文数据库（CJFD）等数据库，并通过其他途径全面收集文献，采用诊断性试验准确性质量评价工具（QUADAS）标准评价文献质量，用Meta‐Disc软件制作综合受试者工作特征（SROC）曲线，评价科玛嘉显色培养基鉴别常见致病性念珠菌的准确性。结果纳入符合标准的文献7篇。7篇文献均报道了科玛嘉念珠菌培养基检测白色念珠菌的准确性，总灵敏度和总特异度分别为98．3％、98．8％，SROC曲线下面积（AUC）为0．9980；6篇文章报道了科玛嘉念珠菌培养基检测热带念珠菌的准确性，总灵敏度和总特异度分别为92．5％、99．8％，A U C为0．9983；5篇文章报道了科玛嘉念珠菌培养基检测光滑念珠菌的准确性，总灵敏度和总特异度分别为98．3％、98．7％，A U C为0．9968。结论科玛嘉培养基能快速鉴定临床常见念珠菌，鉴定结果准确可靠。
목적：평개과마가념주균배양기감별상견치병성념주균적준학성。방법검색MEDLINE、EMBase、중국생물의학문헌수거고（CBM ）、중문과기기간전문수거고（CSJD）、중국기간전문수거고（CJFD）등수거고，병통과기타도경전면수집문헌，채용진단성시험준학성질량평개공구（QUADAS）표준평개문헌질량，용Meta‐Disc연건제작종합수시자공작특정（SROC）곡선，평개과마가현색배양기감별상견치병성념주균적준학성。결과납입부합표준적문헌7편。7편문헌균보도료과마가념주균배양기검측백색념주균적준학성，총령민도화총특이도분별위98．3％、98．8％，SROC곡선하면적（AUC）위0．9980；6편문장보도료과마가념주균배양기검측열대념주균적준학성，총령민도화총특이도분별위92．5％、99．8％，A U C위0．9983；5편문장보도료과마가념주균배양기검측광활념주균적준학성，총령민도화총특이도분별위98．3％、98．7％，A U C위0．9968。결론과마가배양기능쾌속감정림상상견념주균，감정결과준학가고。
Objective To evaluate the accuracy of CHROMagar Candida medium in identifying common Candida species .Meth‐ods Articles were extensively collected by searching the databases of MEDLINE and EMBase ,the Chinese Biomedical Database (CBM ) ,the Chinese Scientific Journals Database (CSJD) ,the Chinese Journal Full Text Database (CJFD) and through other ways . The qualities of these articles were assessed by using the quality assessment of diagnostic accuracy studies(QUADAS) .At last , summary receiver operating characteristic (SROC) curve was performed by the Meta‐Disc software ,so as to summarize diagnostic accuracy of CHROMagar Candida medium in identifying common Candida species .Results A total of 7 articles meeting all criteria were enrolled in this study .All 7 articles reported the accuracy of CHROMagar Candida medium in identifying the Candida albi‐cans ,the pooled sensitivity and specificity was 98 .3% and 98 .8% respectively ,and area under SROC curve (AUC) was 0 .998 0 .A‐mong them ,6 articles reported the accuracy of CHROMagar Candida medium in identifying Candida tropicalis ,the pooled sensitivity and specificity was 92 .5% and 99 .8% respectively ,and the AUC was 0 .998 3 .Among them ,5 articles reported the accuracy of CHROMagar Candida medium in identifying Candida Glabrata ,the pooled sensitivity and specificity was 98 .3% and 98 .7% respec‐tively ,and the AUC was 0 .996 8 .Conclusion CHROMagar Candida medium could quickly identify clinical common Candida species and results are reliable .