CAJ | 학술논문

目的观察同种异体角膜基质透镜植入术矫治远视眼的安全性、有效性和预测性.方法病例系列研究.对21例(37只眼)远视患者行同种异体角膜基质透镜植入术.术前远视度数为3.25～ 10.00 D,平均(6.84±2.79)D.术后随访3个月,观察裸眼远近视力、最佳矫正视力和屈光度的矫治情况,并采用角膜地形图、OCT、眼反应仪等观察手术后角膜形态及角膜生物力学的改变.数据采用方差分析.结果术中术后无严重并发症.术后裸眼远近视力较术前均有明显改善.术后3个月裸眼远视力为(4.89±0.10),明显优于术前的4.64±0.25(F=5.919,P＜0.001);3个月裸眼近视力为J1.18,较术前J4.94明显提高(F=4.926,P＜0.01),且术后3个月31只眼(83.8％)术后裸眼近视力为J1.术后早期呈轻度过矫状态,术后1个月左右屈光度数稳定;术后3个月,平均残余等效球镜度数为(-0.63±0.94)D,较术前(6.84±2.79)D明显下降,术后3个月与术后1个月比较未见明显远视回退现象.术后1周、1个月及3个月角膜生物力学参数与术前比较未见明显下降.结论同种异体角膜基质透镜植入术矫治远视早期安全、有效,预测性好,为远视患者提供了新的手术方式选择.
목적 관찰동충이체각막기질투경식입술교치원시안적안전성、유효성화예측성.방법 병례계렬연구.대21례(37지안)원시환자행동충이체각막기질투경식입술.술전원시도수위3.25～ 10.00 D,평균(6.84±2.79)D.술후수방3개월,관찰라안원근시력、최가교정시력화굴광도적교치정황,병채용각막지형도、OCT、안반응의등관찰수술후각막형태급각막생물역학적개변.수거채용방차분석.결과 술중술후무엄중병발증.술후라안원근시력교술전균유명현개선.술후3개월라안원시력위(4.89±0.10),명현우우술전적4.64±0.25(F=5.919,P＜0.001);3개월라안근시력위J1.18,교술전J4.94명현제고(F=4.926,P＜0.01),차술후3개월31지안(83.8％)술후라안근시력위J1.술후조기정경도과교상태,술후1개월좌우굴광도수은정;술후3개월,평균잔여등효구경도수위(-0.63±0.94)D,교술전(6.84±2.79)D명현하강,술후3개월여술후1개월비교미견명현원시회퇴현상.술후1주、1개월급3개월각막생물역학삼수여술전비교미견명현하강.결론 동충이체각막기질투경식입술교치원시조기안전、유효,예측성호,위원시환자제공료신적수술방식선택.
Objective To evaluate the safety,effectiveness and predictability of allogeneic corneal lens inlays in correcting hyperopia.Methods In this case series study.Twenty-one hyperopic patients (37 eyes) received allogeneic corneal lens inlays.The range of preoperative spherical equivalent was 3.25 to 10.00 D,and the mean value was (6.84±2.79)D.All the cases were followed up for 3 months.Uncorrected and best corrected visual acuity and refraction were compared before and after operation.Corneal topography and optical coherence tomography were performed.Ocular response analyzer was used to evaluate the shifts of corneal hysteresis.Results No intraoperative or postoperative complications were found.Uncorrected distance and near visual acuities (UCDVA and UCNVA) were improved obviously after surgery UCDVA was improved from (4.64±0.25) to (4.89±0.14)(F=5.919,P＜0.001),and UCNVA was improved from J4.94 to J 1.18 (F=4.926,P＜0.01).The UCNVA in 31 eyes (83.8％) was J1 at 3 months after surgery.Mild overcorrection was the state early after operation,and the refractive power was stable at 1 month after surgery.The average residual spherical equivalent was (-0.63 ± 0.94)D,which was improved significantly from (6.84 ± 2.79)D before surgery.There was no obvious hyperopic regression.The corneal biomechanics did not change before and after surgery.Conclusions Allogeneic corneal lens inlays can be used to correct hyperopic eyes with good safety,effectiveness and predictability.It provides a new choice for hyperopic patients.