CAJ | 학술논문

目的：探讨育泡饮对促排卵周期夫精人工授精（ AIH）患者卵泡周围血流的影响。方法将60例接受AIH助孕并符合小卵泡排卵诊断的不孕症患者，随机分为对照组34例与治疗组26例。对照组行氯米芬促排卵，治疗组在氯米芬促排卵同时加服育泡饮。比较2组患者人绒毛膜促性腺激素（ HCG）注射日卵泡周围血流参数之搏动指数（ PI）、抗性指数（ RI）及妊娠率。结果治疗组与对照组比较，HCG注射日卵泡周围血流明显增加（ P＜0．05）；治疗组临床妊娠率为34．61％（9／26），周期妊娠率19.56％（9／46）、对照组分别为11．76％（4／34）和6．06％（4／66），差异有统计学意义（ P＜0．05）。结论补肾法配合氯米芬明显提高AIH患者临床妊娠率，可能与其增加卵泡周围血流灌注、改善卵子质量有关。
목적：탐토육포음대촉배란주기부정인공수정（ AIH）환자란포주위혈류적영향。방법장60례접수AIH조잉병부합소란포배란진단적불잉증환자，수궤분위대조조34례여치료조26례。대조조행록미분촉배란，치료조재록미분촉배란동시가복육포음。비교2조환자인융모막촉성선격소（ HCG）주사일란포주위혈류삼수지박동지수（ PI）、항성지수（ RI）급임신솔。결과치료조여대조조비교，HCG주사일란포주위혈류명현증가（ P＜0．05）；치료조림상임신솔위34．61％（9／26），주기임신솔19.56％（9／46）、대조조분별위11．76％（4／34）화6．06％（4／66），차이유통계학의의（ P＜0．05）。결론보신법배합록미분명현제고AIH환자림상임신솔，가능여기증가란포주위혈류관주、개선란자질량유관。
Objective To explore the effects of Yupao decoction ( YPD) , a Chinese herbal compound formulated by the method of reinforcing kidney, on the follicle blood flow and pregnancy rate in patients undergoing artificial insemination by husband ( AIH ) .Methods Altogether 60 infertile women with small follicular ovulation undergoing AIH were divided into control group( n=34) and YPD group( n=26 ) according to random number table.Patients in control group were induced ovulation by clomiphene, and those of YPD group were taken ovulation induction with orally administration YPD.The pulsatility in-dex ( PI) and resistant index ( RI) of follicle blood flow at the day of HCG injection and pregnancy rate ( PR) were observed.Results PI , RI , PR were dramatically higher in YPD group than those of con-trol group(P<0.05).In YPD group, the clinical PR was 34.61%(9/26)and cycle PR was 19.56%(9/46), by the contrast, the clinical PR was 11.76%(4/34) and the cycle PR 6.06%(4/66)in con-trol group.Conclusion TCM kidney-reinforcing method combined with clomiphene could significantly improve the clinical pregnancy rate of patients undergoing AIH.The potential mechanism of combined therapy would exist in the improve ment the follicle quality by increasing follicle blood flow.