CAJ | 학술논문

【目的】分析和监测急性肠炎患儿细胞及体液免疫功能的变化。【方法】选取2008年1月至2013年12月本院收治的急性肠炎患儿50例作为观察组,选取同期50例经本院门诊体检显示为健康儿童作为对照组,测定两组儿童的 T 淋巴细胞亚群、血清免疫球蛋白及红细胞免疫功能,并进行比较。【结果】T 淋巴细胞亚群的检测结果比较显示,观察组患儿病发期间 CD3+、CD4+百分率较对照组明显降低(P <0.05)；血清IgG、IgA、IgM 比较显示,观察组患儿病发期间血清 IgG、IgA、IgM 含量均明显低于对照组(P <0.05)；红细胞免疫功能测定结果比较显示,观察组患儿病发期间 RBC-CR1R 明显低于对照组(P <0.05),RBC-ICR 两组之间比较无显著性差异(P >0.05)。【结论】急性肠炎患儿细胞免疫和体液免疫功能发生了明显紊乱,其可能参与了急性肠炎的感染过程；治疗时应维持患儿的免疫功能稳定,以期提高患儿抗感染能力。
【목적】분석화감측급성장염환인세포급체액면역공능적변화。【방법】선취2008년1월지2013년12월본원수치적급성장염환인50례작위관찰조,선취동기50례경본원문진체검현시위건강인동작위대조조,측정량조인동적 T 림파세포아군、혈청면역구단백급홍세포면역공능,병진행비교。【결과】T 림파세포아군적검측결과비교현시,관찰조환인병발기간 CD3+、CD4+백분솔교대조조명현강저(P <0.05)；혈청IgG、IgA、IgM 비교현시,관찰조환인병발기간혈청 IgG、IgA、IgM 함량균명현저우대조조(P <0.05)；홍세포면역공능측정결과비교현시,관찰조환인병발기간 RBC-CR1R 명현저우대조조(P <0.05),RBC-ICR 량조지간비교무현저성차이(P >0.05)。【결론】급성장염환인세포면역화체액면역공능발생료명현문란,기가능삼여료급성장염적감염과정；치료시응유지환인적면역공능은정,이기제고환인항감염능력。
[Objective]To analyze and monitor the changes of cellular and humoral immune function in children suffering from acute enteritis.[Methods]Totally 50 children with acute enteritis in our hospital from Jan.2008 to Dec.2013 were chosen as the observation group.Meanwhile,50 healthy children by physical ex-amination in clinic service were chosen as the control group.The T-lymphocyte subsets,serum immunoglobu-lin and red blood cell immune function of two groups were measured and compared.[Results]Compared with the control group,the percentages of CD3 + and CD4 + of children in the observation group during the onset were decreased obviously(P <0.05).Serum IgG,IgA and IgM of children in the observation group during the onset were obviously lower than those in control group(P <0.05).The results of red blood cell immune func-tion measurement showed that RBC-CR1R of children in observation group during the onset was obviously lower than that in control group(P <0.05),but there was no significant difference in RBC-ICR between two groups(P >0.05 ).[Conclusion]The cellular and humoral immune function of children with acute enteritis have obvious disorder,which may be involve in the process of acute enteritis infection.The immune function of patients should be maintained during the treatment in order to improve the antiinfection ability of pediatric pa-tients.