神经损伤与功能重建
神經損傷與功能重建
신경손상여공능중건
Neural Injury and Functional Reconstruction
2015年
5期
403-405
,共3页
抗N-甲基-D 天门冬氨酸受体脑炎%自身免疫性脑炎%核磁共振%脑脊液
抗N-甲基-D 天門鼕氨痠受體腦炎%自身免疫性腦炎%覈磁共振%腦脊液
항N-갑기-D 천문동안산수체뇌염%자신면역성뇌염%핵자공진%뇌척액
anti-N-methyl-D-aspartate receptor encephalitis%autoimmune encephalitis%magnetic resonance imag-ing%cerebrospinal fluid
目的：探讨抗 NMDA 受体脑炎的临床表现、磁共振（MRI）图像及脑脊液特点。方法：回顾性分析我院11例抗 NMDA 受体脑炎患者的临床资料。结果：11例患者主要表现为精神症状、癫痫发作、运动障碍等；头部 MRI 检查无特异性；2例女性患者腹部 CT 发现畸胎瘤；11例患者脑脊液抗 NMDA 抗体（+）。结论：以精神行为异常、癫痫发作、运动障碍为主要表现的青年脑炎患者，要警惕抗 NMDA 受体脑炎的可能，需及时行脑脊液抗 NMDA 抗体检测。
目的：探討抗 NMDA 受體腦炎的臨床錶現、磁共振（MRI）圖像及腦脊液特點。方法：迴顧性分析我院11例抗 NMDA 受體腦炎患者的臨床資料。結果：11例患者主要錶現為精神癥狀、癲癇髮作、運動障礙等；頭部 MRI 檢查無特異性；2例女性患者腹部 CT 髮現畸胎瘤；11例患者腦脊液抗 NMDA 抗體（+）。結論：以精神行為異常、癲癇髮作、運動障礙為主要錶現的青年腦炎患者，要警惕抗 NMDA 受體腦炎的可能，需及時行腦脊液抗 NMDA 抗體檢測。
목적：탐토항 NMDA 수체뇌염적림상표현、자공진（MRI）도상급뇌척액특점。방법：회고성분석아원11례항 NMDA 수체뇌염환자적림상자료。결과：11례환자주요표현위정신증상、전간발작、운동장애등；두부 MRI 검사무특이성；2례녀성환자복부 CT 발현기태류；11례환자뇌척액항 NMDA 항체（+）。결론：이정신행위이상、전간발작、운동장애위주요표현적청년뇌염환자，요경척항 NMDA 수체뇌염적가능，수급시행뇌척액항 NMDA 항체검측。
Objective: To explore the characteristics of clinical presentations, magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) of Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis. Methods: The clinical data of 11 patients with anti-NMDA receptor encephalitis, were retrospectively analyzed. Results: Eleven patients presented with psychiatric symptoms, epilepsy and movement disorders. MRI did not show specific changes. Two female patients suffered from teratoma. All patients were diagnosed by the presence of antibodies to the anti-NMDA receptor in CSF. Conclusion: The young cases with encephalitis, who presented with psychiatric symptoms, epilepsy and movement disorders, may hint at anti-NMDA receptor encephalitis. Timely autoantibody detection is necessary.
