CAJ | 학술논문

目的：调查西安市健康成人乙型肝炎病毒（HBV ）和丙型肝炎病毒（HCV ）的感染状况，为乙、丙型肝炎防治及健康教育提供依据。方法采用多阶段分层随机抽样在西安市10个社区抽取1052例健康成人，检测 HBV 6项血清学标志物和抗‐HCV抗体，分析HBV及HCV感染的分布特征。结果共检出乙型肝炎表面抗原（HBsAg ）阳性37例，总阳性率为3．52％，男性阳性率为4．08％，女性阳性率为3．07％，男、女比较差异无统计学意义（ P＞0．05）；除30～＜40岁与40～＜50岁年龄段男性，其余各年龄段及各年龄段性别间HBsAg阳性率比较差异均无统计学意义（P＞0．05）；检出 HBsAg、乙型肝炎e抗体（HBeAb）和乙型肝炎核心抗体（HBcAb）阳性31例，阳性率为2．95％，单乙型肝炎表面抗体（HBsAb）阳性率为54．18％，各相同血清学模式男、女所占百分率比较，差异均无统计学意义（P＞0．05）。检出抗‐HCV抗体阳性9例（0．86％），男性阳性率为0．64％，女性阳性率为1．02％，男、女阳性率差异无统计学意义（P＞0．05）。结论西安市健康成人HBV、HCV感染率较低，但仍需进一步加强健康教育，定期进行常规传染病的监测与疫苗接种，以控制乙、丙型肝炎。
목적：조사서안시건강성인을형간염병독（HBV ）화병형간염병독（HCV ）적감염상황，위을、병형간염방치급건강교육제공의거。방법채용다계단분층수궤추양재서안시10개사구추취1052례건강성인，검측 HBV 6항혈청학표지물화항‐HCV항체，분석HBV급HCV감염적분포특정。결과공검출을형간염표면항원（HBsAg ）양성37례，총양성솔위3．52％，남성양성솔위4．08％，녀성양성솔위3．07％，남、녀비교차이무통계학의의（ P＞0．05）；제30～＜40세여40～＜50세년령단남성，기여각년령단급각년령단성별간HBsAg양성솔비교차이균무통계학의의（P＞0．05）；검출 HBsAg、을형간염e항체（HBeAb）화을형간염핵심항체（HBcAb）양성31례，양성솔위2．95％，단을형간염표면항체（HBsAb）양성솔위54．18％，각상동혈청학모식남、녀소점백분솔비교，차이균무통계학의의（P＞0．05）。검출항‐HCV항체양성9례（0．86％），남성양성솔위0．64％，녀성양성솔위1．02％，남、녀양성솔차이무통계학의의（P＞0．05）。결론서안시건강성인HBV、HCV감염솔교저，단잉수진일보가강건강교육，정기진행상규전염병적감측여역묘접충，이공제을、병형간염。
Objective To investigate the infection status of hepatitis B virus(HBV) and hepatitis C virus(HCV) in healthy adult in Xi′an ,in order to provide references for hepatitis prevention and health education .Methods A total of 1 052 healthy adults from 10 communities in Xi′an were collected by using multistage stratified random sampling method .HBV serum markers and anti‐HCV antibody were detected ,and characteristics of distribution of HBV and HCV infection were analysed .Results A total of 37 adults were observed with positive hepatitis B surface antigen(HBsAg) ,the total positive rate was 3 .52% ,and the positive rate of male and female was 4 .08% and 3 .07% respectively ,no statistically significant difference was found between male and female(P>0 .05) .Apart from male adults aged 30 - < 40 and 40 - < 50 ,there were no statistically significant differences between each age groups in male and female ,and between female and male in the same age groups(P> 0 .05) .A total of 31 adults were observed with HBsAg ,hepatitis B e antibody (HBeAg)and hepatitis B core antibody(HBcAb) positive ,the positive rate was 2 .95% .The positive rate of hepatitis B surface antibody(HBsAb) was 54 .18% .Serological patterns between different gender had no statistically signifi‐cant differences(P>0 .05) .A total of 9 adults(0 .86% ) were observed with positive anti‐HCV antibody ,and the positive rate of male and female was 0 .64% and 1 .02% respectively ,no statistically significant difference was found between male and female(P>0 .05) .Conclusion Healthy adults in Xi′an have relatively low infection rates of HBV and HCV ,while for the control of hepatitis B and hepatitis C ,further strengthening the health education ,improving awareness of prevention and routine monitoring infectious dis‐eases and vaccination may still be necessary .