CAJ | 학술논문

目的：评价激光立体成形（LSF）的多孔钛对成骨细胞的生物相容性。方法：将 SD 大鼠成骨细胞接种于材料表面进行培养，对不同培养时间点成骨细胞在材料表面的黏附、增殖及 ALP 活性进行检测，并观察细胞形态。以经喷砂粗化处理的致密纯钛作为对照，用 SPSS 对试验结果进行统计分析。结果：培养2、3 h 时实验组细胞贴附率高于对照组（P ＜0．05），4、7 d时细胞增殖和 ALP 活性明显高于对照组（P ＜0．05）。结论：激光成形的多孔钛材料具有良好的骨组织生物相容性。
목적：평개격광입체성형（LSF）적다공태대성골세포적생물상용성。방법：장 SD 대서성골세포접충우재료표면진행배양，대불동배양시간점성골세포재재료표면적점부、증식급 ALP 활성진행검측，병관찰세포형태。이경분사조화처리적치밀순태작위대조，용 SPSS 대시험결과진행통계분석。결과：배양2、3 h 시실험조세포첩부솔고우대조조（P ＜0．05），4、7 d시세포증식화 ALP 활성명현고우대조조（P ＜0．05）。결론：격광성형적다공태재료구유량호적골조직생물상용성。
Objective:To study the biocompatibility of porous Ti processed by laser solid forming(LSF)with osteoblasts.Methods:SD rat osteoblasts were seeded on porous Ti surface processed by LSF.Adhesion,proliferation and ALP activity of the osteoblasts were measured at different time,and all samples were observed under SEM.Dense sand-blasted Ti sheets were used as the controls.All data were statistically analyzed.Results:Adhered cells on porous Ti were more than those on nonporous Ti sheets after 2 and 3 hours of culture(P <0.05).At 4 and 7 days,cell proliferation and ALP activity were significantly higher on porous Ti than those on the controls(P <0.05).Conclusion:Porous Ti processed by LSF possesses good biocompatibility with osteoblasts.