CAJ | 학술논문

目的：探讨无抽搐电休克治疗（ MECT）对精神分裂症患者记忆的远期影响。方法选取至少6个月前接受过MECT的精神分裂症患者40例为MECT组，从未接受过MECT的精神分裂症患者40例为非MECT组，健康人群40例为对照组，采用自编的主观记忆评估问卷、认知功能成套测验（ MCCB）及词汇记忆测验视觉版（ WMT）进行评估。结果MECT组和非MECT组PANSS评分高于对照组（P＜0．05），GAF评分低于对照组（P＜0．05）；MECT组和非MECT组数字序列、空间广度、言语记忆、视觉记忆、即时再认、延迟再认、一致性、主观记忆评估评分均低于对照组（P＜0．05），除视觉记忆得分外，MECT组上述各项评分低于非MECT组（P＜0．05）。结论 MECT可能对精神分裂症患者的记忆功能有远期影响。
목적：탐토무추휵전휴극치료（ MECT）대정신분렬증환자기억적원기영향。방법선취지소6개월전접수과MECT적정신분렬증환자40례위MECT조，종미접수과MECT적정신분렬증환자40례위비MECT조，건강인군40례위대조조，채용자편적주관기억평고문권、인지공능성투측험（ MCCB）급사회기억측험시각판（ WMT）진행평고。결과MECT조화비MECT조PANSS평분고우대조조（P＜0．05），GAF평분저우대조조（P＜0．05）；MECT조화비MECT조수자서렬、공간엄도、언어기억、시각기억、즉시재인、연지재인、일치성、주관기억평고평분균저우대조조（P＜0．05），제시각기억득분외，MECT조상술각항평분저우비MECT조（P＜0．05）。결론 MECT가능대정신분렬증환자적기억공능유원기영향。
Objective To explore the long-term impact of Modified Electric Convulsive Therapy ( MECT ) on memory in patientwithschizophrenia.Methods 40schizophrenicpatientswhohadbeentreatedwithMECTatleast6monthsago(MECT group), 40 schizoprenic patients never treated with MECT (non-MECT group) and 40 healthy controls (control group) were assessed with self-designed subjective memory questionnaire, Matrics Consensus Cognitive Battery ( MCCB) and Word Memory Test ( WMT) .Results Compared with control group, MECT group and non-MECT group showed significantly higher score of PANSS (P<0.05) and significantly lower score of GAF (P<0.05).Scores of digit sequence, spatial span, verbal memory, visual memory, instant recognition, delayed recognition, consistency, subjective memory assessment in MECT group and non-MECT group were significantly lower than those in control group (P<0.05).Scores of all above-mentioned tests except visual memory in MECT group were significantly lower than those in non-MECT group (P<0.05).Conclusion MECT may has long-term negative effect on the mnemonic function in patients with schizophrenia.