CAJ | 학술논문

目的：运用事件相关电位（ERP）探索言语工作记忆负荷关联的神经网络演化。方法21名被试者按键完成言语材料的延迟匹配样本任务，工作记忆负荷分别是3和5个字母，分析工作记忆容量（WMC）及19通道ERP统计参数映像（SPM）的时空模式。结果高负荷（3.30±0.76）vs低负荷（2.48±0.30），WMC差异有统计学意义（t=5.950, P=0.000）。SPM显示：编码期的负荷效应相继出现在右腹侧、背侧注意网络和左额颞顶语言区；维持期的负荷效应出现在右腹侧注意网络，先后与背侧注意网络和左额颞区相伴。结论在言语工作记忆负荷超出其有限容量时，右腹侧注意网络可能参与防止项目之间混淆和言语长时记忆的激活。
목적：운용사건상관전위（ERP）탐색언어공작기억부하관련적신경망락연화。방법21명피시자안건완성언어재료적연지필배양본임무，공작기억부하분별시3화5개자모，분석공작기억용량（WMC）급19통도ERP통계삼수영상（SPM）적시공모식。결과고부하（3.30±0.76）vs저부하（2.48±0.30），WMC차이유통계학의의（t=5.950, P=0.000）。SPM현시：편마기적부하효응상계출현재우복측、배측주의망락화좌액섭정어언구；유지기적부하효응출현재우복측주의망락，선후여배측주의망락화좌액섭구상반。결론재언어공작기억부하초출기유한용량시，우복측주의망락가능삼여방지항목지간혼효화언어장시기억적격활。
Objective To explore the influence of verbal working memory load on associative neural networks. Methods Twenty-one subjects were required to complete a verbal delayed matching-to-sample task under the condition of low (3 items) or high (5 items) working memory load (WML). The 19-channels event-related potentials (ERP) were analyzed with statistical parametric mapping. Results A significant difference in working memory capacity (WMC) was found between low WML and high WML groups [2.48 ± 0.30 vs 3.30 ± 0.76; t(20)=5.950, P=0.000]. Statistical parametric mapping revealed that during the encoding stage, the effects of WML appeared in succession in the right ventral attention network (rVAN), the dorsal attention network, and the language areas in the left hemisprere. During the maintenance stage, the effects WML occured in the rVAN acompanied by either DAN or left frontal-temporal regions. Conclusions When the WML is beyond the WMC, the rVAN may participate in the prevention of interference among items and in the activation of long-term memory.