中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
Chinese Journal of Information on Traditional Chinese Medicine
2015年
10期
28-30
,共3页
复方苦参注射液%肺癌疼痛%盐酸羟考酮%近期疗效
複方苦參註射液%肺癌疼痛%鹽痠羥攷酮%近期療效
복방고삼주사액%폐암동통%염산간고동%근기료효
Compound Sophorae Flavescentis Radix Injection%lung cancer pain%oxycodone hydrochloride%near-term efficacy
目的：观察复方苦参注射液联合盐酸羟考酮治疗肺癌疼痛的近期疗效。方法将60例中晚期肺癌疼痛患者随机分为治疗组和对照组各30例。对照组给予最佳对症支持治疗联合盐酸羟考酮，治疗组在对照组基础上给予复方苦参注射液20 mL加入0.9%氯化钠注射液250 mL中静脉滴注，每日1次，连用14 d。观察2组患者治疗前后卡氏评分、疼痛程度及不良反应。结果治疗组治疗后疼痛得到明显缓解(P＜0.01)，对照组疼痛程度治疗前后比较差异无统计学意义(P＞0.05)，治疗后组间比较差异无统计学意义(P＞0.05)。治疗组治疗后卡氏评分明显高于治疗前及对照组，差异均有统计学意义(P＜0.05)；对照组治疗前后卡氏评分差异无统计学意义(P＞0.05)。结论复方苦参注射液联合盐酸羟考酮能明显缓解中晚期肺癌患者疼痛，提高生活质量，且无明显不良反应。
目的：觀察複方苦參註射液聯閤鹽痠羥攷酮治療肺癌疼痛的近期療效。方法將60例中晚期肺癌疼痛患者隨機分為治療組和對照組各30例。對照組給予最佳對癥支持治療聯閤鹽痠羥攷酮，治療組在對照組基礎上給予複方苦參註射液20 mL加入0.9%氯化鈉註射液250 mL中靜脈滴註，每日1次，連用14 d。觀察2組患者治療前後卡氏評分、疼痛程度及不良反應。結果治療組治療後疼痛得到明顯緩解(P＜0.01)，對照組疼痛程度治療前後比較差異無統計學意義(P＞0.05)，治療後組間比較差異無統計學意義(P＞0.05)。治療組治療後卡氏評分明顯高于治療前及對照組，差異均有統計學意義(P＜0.05)；對照組治療前後卡氏評分差異無統計學意義(P＞0.05)。結論複方苦參註射液聯閤鹽痠羥攷酮能明顯緩解中晚期肺癌患者疼痛，提高生活質量，且無明顯不良反應。
목적：관찰복방고삼주사액연합염산간고동치료폐암동통적근기료효。방법장60례중만기폐암동통환자수궤분위치료조화대조조각30례。대조조급여최가대증지지치료연합염산간고동，치료조재대조조기출상급여복방고삼주사액20 mL가입0.9%록화납주사액250 mL중정맥적주，매일1차，련용14 d。관찰2조환자치료전후잡씨평분、동통정도급불량반응。결과치료조치료후동통득도명현완해(P＜0.01)，대조조동통정도치료전후비교차이무통계학의의(P＞0.05)，치료후조간비교차이무통계학의의(P＞0.05)。치료조치료후잡씨평분명현고우치료전급대조조，차이균유통계학의의(P＜0.05)；대조조치료전후잡씨평분차이무통계학의의(P＞0.05)。결론복방고삼주사액연합염산간고동능명현완해중만기폐암환자동통，제고생활질량，차무명현불량반응。
Objective To observe the near-term efficacy of Compound Sophorae Flavescentis Radix Injection combined with oxycodone hydrochloride in treating lung cancer pain.Methods Sixty patients with advanced lung cancer were randomly divided into treatment group (30 cases) and control group (30 cases). The control group was treated by the best symptomatic and supportive treatment combined with oxycodone hydrochloride, while the treatment group was treated by Compound Sophorae Flavescentis Radix Injection 20 mL which was added into 250 mL normal saline solution for intravenous drip additionally, once a day for 14 days. KPS score before and after treatment, analgesic effect, and adverse action of the two groups were observed.Results After treatment, the pain in patients of treatment group was significantly improved (P<0.01), but it was not statistically different compared with the control group (P>0.05). KPS in patients of treatment group was significantly improved compared with that of before treatment and the comrol group, with statistical significance (P>0.05). There was no statistical significance in KPS score between before and after treatment of the control group (P>0.05).Conclusion Compound Sophorae Flavescentis Radix Injection combine with oxycodone hydrochloride can significantly relieve patients’ pain and improve their life quality, with no obvious adverse reactions.
