CAJ | 학술논문

目的：探讨重复经颅磁刺激（ rTMS）对甲基苯丙胺依赖者焦虑及心理渴求症状的疗效。方法将112例甲基苯丙胺依赖患者随机分为研究组和对照组，研究组接受系统的rTMS治疗，对照组接受类似rTMS 的假性刺激治疗，共8周。在基线及治疗后第1、2、4、6、8周末应用焦虑自评量表（ SAS）和视觉模拟标尺（ VAS）评定患者的焦虑症状和心理渴求状况。结果治疗后第1、2、4、6、8周末，研究组SAS评分及VAS评分较基线评分均降低（P＜0．05），对照组治疗后第4、6、8周末SAS、VAS评分较基线时降低（P＜0．05），研究组治疗后第1、2、4、6、8周末SAS评分及VAS评分均低于对照组（P＜0．05）。结论 rTMS可显著改善甲基苯丙胺依赖患者的焦虑症状与心理渴求状况，安全性高。
목적：탐토중복경로자자격（ rTMS）대갑기분병알의뢰자초필급심리갈구증상적료효。방법장112례갑기분병알의뢰환자수궤분위연구조화대조조，연구조접수계통적rTMS치료，대조조접수유사rTMS 적가성자격치료，공8주。재기선급치료후제1、2、4、6、8주말응용초필자평량표（ SAS）화시각모의표척（ VAS）평정환자적초필증상화심리갈구상황。결과치료후제1、2、4、6、8주말，연구조SAS평분급VAS평분교기선평분균강저（P＜0．05），대조조치료후제4、6、8주말SAS、VAS평분교기선시강저（P＜0．05），연구조치료후제1、2、4、6、8주말SAS평분급VAS평분균저우대조조（P＜0．05）。결론 rTMS가현저개선갑기분병알의뢰환자적초필증상여심리갈구상황，안전성고。
Objective To explore the effects of repetitive Transcranial Magnetic Stimulation ( rTMS ) to improve anxiety symptoms and psychological craving of patients with methamphetamine dependence.Method A total of 112 patients with methamphetamine dependence were randomly divided into study group with rTMS and control group without rTMS for treatment of 8 weeks.They were assessed with Self-rating Anxiety Scale(SAS)and Visual Analogue Scale(VAS) on baseline, the 1st, 2nd, 4th, 6th and 8th weekend of treatment.Result On the 1st, 2nd, 4th, 6th and 8th weekend of treatment, the scores of SAS and VAS in study group were significantly lower than those on baseline (P<0.05), and were significantly lower than those in control group (P<0.05).On the 4th 6th and 8th weekend of treatment,the scores of SAS and VAS in control group were significantly lower than those on baseline ( P <0.05 ) .Conclusion It is effective and safe for rTMS to improve anxiety symptoms and psychological craving of patients with methamphetamine dependence.