CAJ | 학술논문

目的：探讨缺血性脑卒中患者早期神经功能恶化的相关危险因素。方法选取本院2013年4月~2015年1月收治的80例缺血性脑卒中患者作为研究对象，按照是否发生早期神经功能恶化分为早期神经功能恶化组和非早期神经功能恶化组。采用单因素方差分析和多因素Logistic回归分析比较两组的一般资料和各项临床指标，总结发生早期神经功能恶化的相关因素。结果在80例缺血性脑卒中患者中，25例(31.3%)发生早期神经功能恶化。多因素Logistic回归分析显示，NIHSS评分高、颈动脉狭窄≥50%、心房颤动、糖尿病以及高血压都是发生早期神经功能恶化的危险因素(P<0.05)。结论缺血性脑卒中患者发生早期神经功能恶化的危险因素较多，应针对性给予干预措施以改善预后。
목적：탐토결혈성뇌졸중환자조기신경공능악화적상관위험인소。방법선취본원2013년4월~2015년1월수치적80례결혈성뇌졸중환자작위연구대상，안조시부발생조기신경공능악화분위조기신경공능악화조화비조기신경공능악화조。채용단인소방차분석화다인소Logistic회귀분석비교량조적일반자료화각항림상지표，총결발생조기신경공능악화적상관인소。결과재80례결혈성뇌졸중환자중，25례(31.3%)발생조기신경공능악화。다인소Logistic회귀분석현시，NIHSS평분고、경동맥협착≥50%、심방전동、당뇨병이급고혈압도시발생조기신경공능악화적위험인소(P<0.05)。결론결혈성뇌졸중환자발생조기신경공능악화적위험인소교다，응침대성급여간예조시이개선예후。
Objective To explore the relevant risk factors of early neurological deterioration in patients with ischemic cerebral apoplexy. Methods 80 patients with ischemic cerebral apoplexy in our hospital from April 2013 to January 2015 were selected and divided into the group of early neurological deterioration and the group of non-early neurologi-cal deterioration according to whether early neurological deterioration occurred.Single-factor ANOVA and multi-factor Logistic regression analysis were applied to compare the general data and each clinical index between two groups,and relevant factors for incidence of early neurological deterioration was summarized. Results In 80 patients with ischemic stroke,25 patients (31.3%) had early neurological deterioration.Multi-factor Logistic regression analysis detected that high score of NIHSS,carotid artery stenosis ≥50%,ventricular atrial fibrillation,diabetes and hypertension were all risk factors for early neurological deterioration (P<0.05). Conclusion Risk factors for early neurological deterioration in pa-tients with ischemic cerebral apoplexy are relatively various,and specific intervention measures should be applied so as to improve patients’prognosis.