世界中医药
世界中醫藥
세계중의약
World Chinese Medicine
2015年
9期
1453-1456
,共4页
柴胡疏肝散%抑郁症%临床研究%基础研究
柴鬍疏肝散%抑鬱癥%臨床研究%基礎研究
시호소간산%억욱증%림상연구%기출연구
Chaihu Shugan powder%Depression%Clinical research%Experimental research
柴胡疏肝散是一种临床常用的治疗抑郁症的复方。近年来，国内外学者应用现代科学方法作了大量关于柴胡疏肝散治疗抑郁症的研究。通过检索近年来国内外关于柴胡疏肝散抗抑郁研究的文献，对其相关临床及基础实验研究进行总结，表明柴胡疏肝散具有显著的抗抑郁作用，其机制可能涉及调节单胺类神经递质、保护海马神经元、调整 HPA 轴功能等。本文对于进一步深入研究抑郁症发病机制、新药研发及提高抑郁症的诊疗疗效有一定的参考价值。
柴鬍疏肝散是一種臨床常用的治療抑鬱癥的複方。近年來，國內外學者應用現代科學方法作瞭大量關于柴鬍疏肝散治療抑鬱癥的研究。通過檢索近年來國內外關于柴鬍疏肝散抗抑鬱研究的文獻，對其相關臨床及基礎實驗研究進行總結，錶明柴鬍疏肝散具有顯著的抗抑鬱作用，其機製可能涉及調節單胺類神經遞質、保護海馬神經元、調整 HPA 軸功能等。本文對于進一步深入研究抑鬱癥髮病機製、新藥研髮及提高抑鬱癥的診療療效有一定的參攷價值。
시호소간산시일충림상상용적치료억욱증적복방。근년래，국내외학자응용현대과학방법작료대량관우시호소간산치료억욱증적연구。통과검색근년래국내외관우시호소간산항억욱연구적문헌，대기상관림상급기출실험연구진행총결，표명시호소간산구유현저적항억욱작용，기궤제가능섭급조절단알류신경체질、보호해마신경원、조정 HPA 축공능등。본문대우진일보심입연구억욱증발병궤제、신약연발급제고억욱증적진료료효유일정적삼고개치。
Chaihu Shugan Powder was commonly used for the clinical treatment of depression.In recent years,researchers at home and abroad conducted lots of studies on treatment of depression by applying Chaihu Shugan powder with modern scientific methods.Through searching domestic and oversea lectures which studied on treatment of depression by applying Chaihu Shugan powder published in recent years,this article summarized relative clinical and fundamental experimental studies and indicated that that Chaihu Shugan powder had remarkable antidepressant effect.The mechanism may involve regulating monoamine neurotransmit-ter,protecting hippocampal neurons and adjusting HPA axis.This article could provide reference for a further study on pathogene-sis of depression,new drug development and improvement of depression treatment.
