CAJ | 학술논문

目的：优选苦豆子中生物碱减压动态提取工艺。方法：以苦豆子总碱、氧化苦参碱的含量作为评价指标，采用正交优化试验，考察加水量、提取时间、提取次数3个因素的影响，结合综合评分的方法优选苦豆子生物碱减压提取工艺，并与较为常用的常压回流法、煎煮法提取效果相比较。结果：最佳提取工艺为加12倍量水，在温度为60℃条件下动态沸腾减压提取3次，每次1 h。结论：优化的苦豆子生物碱减压提取工艺中总碱及氧化苦参碱的含量均优于常压回流法和煎煮法，且工艺稳定、可行。
목적：우선고두자중생물감감압동태제취공예。방법：이고두자총감、양화고삼감적함량작위평개지표，채용정교우화시험，고찰가수량、제취시간、제취차수3개인소적영향，결합종합평분적방법우선고두자생물감감압제취공예，병여교위상용적상압회류법、전자법제취효과상비교。결과：최가제취공예위가12배량수，재온도위60℃조건하동태비등감압제취3차，매차1 h。결론：우화적고두자생물감감압제취공예중총감급양화고삼감적함량균우우상압회류법화전자법，차공예은정、가행。
This study was aimed to optimize the vacuumextraction technology of alkaloids fromSophora alopecuroides. The orthogonal test and comprehensive evaluation were used to optimize the vacuumextraction technology. Contents of total alkali and oxymatrinewere used as index components for optimizing the effect of three factors, which were the adding amount of water, extraction time, and extraction frequency. Comparison was made among optimal conventional extraction process, decoction extraction and vacuumextraction. The results showed that the optimum extraction process was to add 12 times amount of water, and to extract for 3 times under the temperature of 60℃, 1h for each time. It was concluded that the optimized extraction vacuum technologyof alkaloids fromS. alopecuroidsdecompression total alkali content and oxymatrine process was better than that of optimal conventional extraction process and decoction extraction. The vacuumextraction technology was stable and practical.