安徽医科大学学报
安徽醫科大學學報
안휘의과대학학보
Acta Universitatis Medicinalis Anhui
2015年
10期
1483-1486
,共4页
蔡静玉%王康%徐建华%丁长海
蔡靜玉%王康%徐建華%丁長海
채정옥%왕강%서건화%정장해
骨关节炎%髌骨下脂肪垫%软骨缺损%核磁共振
骨關節炎%髕骨下脂肪墊%軟骨缺損%覈磁共振
골관절염%빈골하지방점%연골결손%핵자공진
osteoarthritis%infrapatellar fat pad%cartilage defect%magnetic resonance imaging
目的 探讨膝骨关节炎( OA )患者髌骨下脂肪垫( IPFP)大小与软骨缺损之间的关系. 方法 收集174例膝OA患者,对患者一般情况行问卷调查,在核磁共振3D脂肪抑制T1加权回波序列上利用Osirix软件测量IPFP容积,在核磁共振T2加权质子密度加权快速自旋回波序列上对软骨缺损进行评级(0~4级),分析IPFP容积与软骨缺损之间的关系. 结果 放射性OA与非放射性OA患者IPFP体积差异无统计学意义;不同严重程度OA患者的IPFP体积差异有统计学意义(P<0. 05);OA患者IPFP体积与性别呈负相关性,与身高、体重呈正相关性,差异有统计学意义(P <0. 05);IPFP体积与膝关节内外侧股骨、外侧胫骨以及髌骨软骨缺损呈负相关性,差异有统计学意义( P<0. 05 ). 结论IPFP体积与软骨缺损及OA的病情严重程度相关, IPFP在OA发生发展中可能起保护作用.
目的 探討膝骨關節炎( OA )患者髕骨下脂肪墊( IPFP)大小與軟骨缺損之間的關繫. 方法 收集174例膝OA患者,對患者一般情況行問捲調查,在覈磁共振3D脂肪抑製T1加權迴波序列上利用Osirix軟件測量IPFP容積,在覈磁共振T2加權質子密度加權快速自鏇迴波序列上對軟骨缺損進行評級(0~4級),分析IPFP容積與軟骨缺損之間的關繫. 結果 放射性OA與非放射性OA患者IPFP體積差異無統計學意義;不同嚴重程度OA患者的IPFP體積差異有統計學意義(P<0. 05);OA患者IPFP體積與性彆呈負相關性,與身高、體重呈正相關性,差異有統計學意義(P <0. 05);IPFP體積與膝關節內外側股骨、外側脛骨以及髕骨軟骨缺損呈負相關性,差異有統計學意義( P<0. 05 ). 結論IPFP體積與軟骨缺損及OA的病情嚴重程度相關, IPFP在OA髮生髮展中可能起保護作用.
목적 탐토슬골관절염( OA )환자빈골하지방점( IPFP)대소여연골결손지간적관계. 방법 수집174례슬OA환자,대환자일반정황행문권조사,재핵자공진3D지방억제T1가권회파서렬상이용Osirix연건측량IPFP용적,재핵자공진T2가권질자밀도가권쾌속자선회파서렬상대연골결손진행평급(0~4급),분석IPFP용적여연골결손지간적관계. 결과 방사성OA여비방사성OA환자IPFP체적차이무통계학의의;불동엄중정도OA환자적IPFP체적차이유통계학의의(P<0. 05);OA환자IPFP체적여성별정부상관성,여신고、체중정정상관성,차이유통계학의의(P <0. 05);IPFP체적여슬관절내외측고골、외측경골이급빈골연골결손정부상관성,차이유통계학의의( P<0. 05 ). 결론IPFP체적여연골결손급OA적병정엄중정도상관, IPFP재OA발생발전중가능기보호작용.
Objective To examine the association between infrapatellar fat pad ( IPFP) volume and cartilage de-fects in patients with knee osteoarthritis ( OA) . Methods 174 subjects participated in this study. The fat sup-pressed 3-dimensional T1-weighted spoiled gradient recall ( SPGR) magnetic resonance imaging ( MRI) was used to measure IPFP volume. T2-weighted fast spin echo MRI was utilized to assess cartilage defects. Results There was no significant difference in IPFP volume between patients with radiographic osteoarthritis and those without radio-graphic osteoarthritis. There were significant differences in IPFP volume among groups with mild, moderate and severe diseased groups ( P<0. 05 ) . IPFP volume was significantly and positively associated with height and weight ( P<0. 05 ) , and men had more IPFP volume than women ( P<0. 05 ) . There were significant and negative associ-ations between IPFP volume and cartilage defects at all sites except for medial tibial site ( P<0. 05 ) . Conclusion IPFP volume is negatively associated with cartilage defects severity in knee OA, suggesting that infrapatellar fat pad may play a protective role in knee OA.