CAJ | 학술논문

目的：探讨热毒宁联合干扰素雾化治疗手足口病的临床疗效和不良反应。方法选择确诊为手足口病患儿128例，将其随机分为观察组与对照组两组，各64例，观察组给予热毒宁注射液联合干扰素雾化治疗，对照组给予利巴韦林注射液治疗，疗程5~7 d，比较分析两组的临床疗效情况。结果观察组的总有效率、平均热退时间及疱疹消失时间与对照组相比较，差异具有明显的统计学意义（P<0.05）。结论热毒宁注射液联合干扰素雾化治疗手足口病的疗效确切，安全性高，值得临床推广应用。
목적：탐토열독저연합간우소무화치료수족구병적림상료효화불량반응。방법선택학진위수족구병환인128례，장기수궤분위관찰조여대조조량조，각64례，관찰조급여열독저주사액연합간우소무화치료，대조조급여리파위림주사액치료，료정5~7 d，비교분석량조적림상료효정황。결과관찰조적총유효솔、평균열퇴시간급포진소실시간여대조조상비교，차이구유명현적통계학의의（P<0.05）。결론열독저주사액연합간우소무화치료수족구병적료효학절，안전성고，치득림상추엄응용。
Objective To discuss clinical effect and adverse reactions of treating hand, foot and mouth disease(HFMD) by reduning injection combined with interferon inhalation.Method choose 128 cases of children definitely diagnosed with HFMD with, and randomly divide them into observation and control group, 64 cases in each. Observation group was treated by reduning injection combined with interferon inhalation treatment, and control group with ribavirin injection with a treatment period of 5-7 days. Compare and analyze clinical effect of both groups.Result Total effective rate, average time of fever abatement and herpes disappearance time of observation group shows obvious difference with statistical significance compared with that of control group(P<0.05).Conclusion Treating HFMD by eduning injection combined with interferon inhalation shows exact curative effect and high safety, which is worthy of clinical application.