CAJ | 학술논문

目的：采用彩色多普勒联合经颅多普勒分析颈动脉颅外段狭窄对脑部供血的影响。方法选择2012年1月~2014年7月于我院经彩色多普勒超声检出的85例颈内动脉单侧狭窄患者，其中轻、中度狭窄者35例，重度狭窄及闭塞者50例，另选择50例颈动脉正常者作为对照组，均行经颅多普勒超声检查。观察各组受检者颅内血管的血流频谱形态、血流速度、搏动指数及侧枝循环建立情况。结果重度狭窄及闭塞组大脑中动脉血流速度及搏动指数低于轻、中度狭窄组及对照组，差异有统计学意义（P<0.05），而轻、中度狭窄组血流速度及搏动指数高于对照组和重度狭窄及闭塞组，差异有统计学意义（P<0.05）。重度狭窄患者中，侧枝循环建立3条者3例，建立2条者14例，建立1条者例13例。结论将彩色多普勒和经颅多普勒超声联合应用，可评价颈动脉狭窄引起的颅内血流动力学改变及侧枝循环建立情况，有利于即时干预，预防缺血性脑卒中的发生。
목적：채용채색다보륵연합경로다보륵분석경동맥로외단협착대뇌부공혈적영향。방법선택2012년1월~2014년7월우아원경채색다보륵초성검출적85례경내동맥단측협착환자，기중경、중도협착자35례，중도협착급폐새자50례，령선택50례경동맥정상자작위대조조，균행경로다보륵초성검사。관찰각조수검자로내혈관적혈류빈보형태、혈류속도、박동지수급측지순배건립정황。결과중도협착급폐새조대뇌중동맥혈류속도급박동지수저우경、중도협착조급대조조，차이유통계학의의（P<0.05），이경、중도협착조혈류속도급박동지수고우대조조화중도협착급폐새조，차이유통계학의의（P<0.05）。중도협착환자중，측지순배건립3조자3례，건립2조자14례，건립1조자례13례。결론장채색다보륵화경로다보륵초성연합응용，가평개경동맥협착인기적로내혈류동역학개변급측지순배건립정황，유리우즉시간예，예방결혈성뇌졸중적발생。
Objective To analyze the influence of internal carotid artery extra-cranial stenosis on blood supply to the brain with application of combination of Doppler ultrasonography and trans-cranial Doppler ultrasonography. Methods Altogether 85 patients with unilateral carotid artery stenosis who had been conifrmed by color Doppler ultrasound from January 2012 to July 2014 were selected, among whom the light and moderate stenosis were found in 35 cases and taken as Light and Moderate Stenosis Group;severe stenosis and occlusion were revealed in 50 cases and taken as Severe Stenosis and Occlusion Group. Moreover, 50 healthy people with normal vascular bilateral intracranial and extra-cranial carotid artery were selected as Control Group. Then, the blood spectrum morphology, blood flow velocity, pulsatility index and collateral circulation were observed. Results The blood lfow velocity and pulsatility index in Severe Stenosis and Occlusion Group were lower than those of Control Group with statistically significant differences (P<0.05). While, Light and Moderate Stenosis Group showed higher blood flow velocity and pulsatility index than Severe Stenosis and Occlusion Group as well as Control Group with statistically signiifcant differences (P<0.05). Among all the patients with severe stenosis and occlusion, the establishment of 3 collateral circulations was seen in 3 cases;the establishment of 2 in 14 cases, the establishment of 1 in 13 cases. Conclusion The combination of Doppler ultrasonography and transcranial Doppler carotid artery stenosis could be used for assessment of intracranial hemodynamics changes and collateral circulation establishment caused by carotid artery stenosis, which was helpful for immediate intervention and prevention of ischemic stroke.