CAJ | 학술논문

目的：通过系列临床研究，体现我科中医药治疗急性脑出血的独特临床优势，并验证我科中医中风病诊疗方案的科学性、实用性、可重复性及可操作性。方法：将120例急性脑出血患者随机分为西医治疗组和中西医结合治疗组。通过对治疗前后血超氧化物歧化酶（Superoxide Dismutase，SOD）、脂质过氧化物血清丙二醛（MDA）、C 反应蛋白（C-reactiVe Pro-tein，CRP）、同型半胱氨酸（Homocysteine，HCY）指标的比较，分析比较2组患者之间在近期疗效方面的差异；通过对2组患者之间治疗前后的神经功能缺损评分、Barthel 指数的比较，分析评价它们之间远期疗效的优劣。结果：近期指标：中西医结合治疗组的 MDA、CRP、HCY 比西医治疗组有明显下降（P ＜0．05），SOD 升高（P ＜0．05），优于西医治疗组。远期指标：中西医结合治疗组的神经功能缺损评分减低、Barthel 指数提高比西医治疗组差异有统计学意义（P ＜0．05）。结论：中西医结合治疗急性出血性脑卒中比单纯西医治疗有明显的优势。
목적：통과계렬림상연구，체현아과중의약치료급성뇌출혈적독특림상우세，병험증아과중의중풍병진료방안적과학성、실용성、가중복성급가조작성。방법：장120례급성뇌출혈환자수궤분위서의치료조화중서의결합치료조。통과대치료전후혈초양화물기화매（Superoxide Dismutase，SOD）、지질과양화물혈청병이철（MDA）、C 반응단백（C-reactiVe Pro-tein，CRP）、동형반광안산（Homocysteine，HCY）지표적비교，분석비교2조환자지간재근기료효방면적차이；통과대2조환자지간치료전후적신경공능결손평분、Barthel 지수적비교，분석평개타문지간원기료효적우렬。결과：근기지표：중서의결합치료조적 MDA、CRP、HCY 비서의치료조유명현하강（P ＜0．05），SOD 승고（P ＜0．05），우우서의치료조。원기지표：중서의결합치료조적신경공능결손평분감저、Barthel 지수제고비서의치료조차이유통계학의의（P ＜0．05）。결론：중서의결합치료급성출혈성뇌졸중비단순서의치료유명현적우세。
Objective:To reflect the unique clinical advantages of Chinese medicine in treating acute cerebral hemorrhage and stroke,and to verify scientific,practical,repeatable and operability treatment programs in our department TCM.Methods:Accord-ing to the random number table,120 cases of patients with acute cerebral hemorrhage in our department were randomly divided into Western medicine treatment group (n =60)and Chinese medicine combine with Western medicine therapy group (n =60).Before and after treatment,blood superoxide dismutase,lipid peroxides in serum MDA,C-reactive protein,homocysteine indicators were observed.The difference between the short-term effect in terms of analysis and comparison of the two groups of patients were con-ducted;through the merits of the neurological deficit scores between the two groups of patients before and after treatment were ob-served,comparing the index,analysis and evaluation of long-term efficacy between them.Results:Recent indicators:Chinese medicine combine with Western medicine treatment group MDA,CRP,HCY decreased significantly (P <0.05)than those in western medicine group,and SOD increased (P <0.05),better than that of western medicine group.Long-term indicators:Chi-nese medicine combine with Western medicine neurological impairment score was lower intreatment group,Barthel index increased significantly differently than Western medicine treatment group (P <0.05).Conclusion:Chinese medicine combine with Western medicine treatment of acute hemorrhagic stroke has a distinct advantage over applying Western medicine alone.